Recombinant Anti-SARS-CoV Antibody (S230.15) (CAT#: HPAB-0103LY)
This product is antibody recognizes SARS-CoV. The antibody S230.15 immunoassay techniques such as: ELISA, RIA.
Specific Inquiry
Inhib
Figure 1 Mapping of neutralizing epitopes on the SARS-CoV S glycoprotein recognized by human MAbs through sequence analysis and cross-competition studies.
Cross-competition of MAbs binding to the SARS-CoV S glycoprotein. Shown are the percentages of inhibition of the binding of 3 biotinylated MAbs (S109.8, S227.14, and S230.15; concentration, 0.1 μg/ml) to the recombinant SARS-CoV S glycoprotein by a panel of 23 unlabeled competing MAbs (at a saturating concentration [5 μg/ml]) belonging to groups I through VI.
Rockx, B., Corti, D., Donaldson, E., Sheahan, T., Stadler, K., Lanzavecchia, A., & Baric, R. (2008). Structural basis for potent cross-neutralizing human monoclonal antibody protection against lethal human and zoonotic severe acute respiratory syndrome coronavirus challenge. Journal of virology, 82(7), 3220-3235.
Inhib
Figure 2 Prophylactic treatment of lethal SARS-CoV infections in 10-week-old BALB/c mice with 25 μg of cross-neutralizing MAbs.
Body weights of mice infected with MA15 were measured daily after passive transfer of 25 μg of MAb S109.8 (+), S227.14 (○), S230.15 (×), or D2.2 (□).
Rockx, B., Corti, D., Donaldson, E., Sheahan, T., Stadler, K., Lanzavecchia, A., & Baric, R. (2008). Structural basis for potent cross-neutralizing human monoclonal antibody protection against lethal human and zoonotic severe acute respiratory syndrome coronavirus challenge. Journal of virology, 82(7), 3220-3235.
Specifications
- Derivation
- Mouse
- Specificity
- SARS-CoV
- Species Reactivity
- SARS-CoV
- Clone
- S230.15
- Applications
- ELISA, RIA, Inhib
Product Property
- Purification
- 95% pure by SDS-PAGE
- Purity
- > 95% Purity determined by SDS-PAGE.
- Format
- Liquid
- Buffer
- PBS, pH 7.4
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.
Applications
- Application Notes
- The SARS-CoV antibody has been reported in applications of Enzyme-linked Immunosorbent Assay, Radioimmunoassay, Inhibition.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-885-S(P) | Recombinant Anti-SARS-CoV Antibody scFv Fragment | RIA, ELISA, FuncS | scFv |
| HPAB-0297CQ-S(P) | Recombinant Human Anti-SARS-CoV Antibody scFv Fragment (HuMAb 03-014) | ELISA, Neut | Human scFv |
| HPAB-S0121-YC-S(P) | Mouse Anti-SARS-CoV Recombinant Antibody (clone F26G19); scFv Fragment | Neut | Mouse scFv |
| HPAB-2048-FY-S(P) | Human Anti-SARS-CoV Recombinant Antibody (clone CR03-014); scFv Fragment | Neut, ELISA, FC | Human scFv |
| HPAB-2049-FY-S(P) | Human Anti-SARS-CoV Recombinant Antibody (clone CR03-022); scFv Fragment | Neut, ELISA, FC | Human scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHH-885-F(E) | Recombinant Human Anti-SARS-CoV Antibody Fab Fragment | IP, RIA, FuncS | Fab |
| HPAB-1909-FY-S(P) | Human Anti-SARS-CoV Recombinant Antibody (clone 03-001); Fab Fragment | ELISA | Human Fab |
| HPAB-1910-FY-S(P) | Human Anti-SARS-CoV Recombinant Antibody (clone 03-002); Fab Fragment | ELISA | Human Fab |
| HPAB-1911-FY-S(P) | Human Anti-SARS-CoV Recombinant Antibody (clone 03-009); Fab Fragment | ELISA | Human Fab |
| HPAB-1912-FY-S(P) | Human Anti-SARS-CoV Recombinant Antibody (clone 03-018); Fab Fragment | ELISA | Human Fab |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-649LC | Mouse Anti-SARS-CoV Recombinant Antibody (MRO-649LC) | ELISA | Mouse antibody |
| MRO-649LC-S(P) | Mouse Anti-SARS-CoV Recombinant Antibody; scFv Fragment (MRO-649LC-S(P)) | ELISA | Mouse scFv |
| MRO-650LC-S(P) | Mouse Anti-SARS-CoV Recombinant Antibody; scFv Fragment (MRO-650LC-S(P)) | ELISA | Mouse scFv |
| MRO-651LC-S(P) | Mouse Anti-SARS-CoV Recombinant Antibody; scFv Fragment (MRO-651LC-S(P)) | ELISA | Mouse scFv |
| MRO-652LC-S(P) | Mouse Anti-SARS-CoV Recombinant Antibody; scFv Fragment (MRO-652LC-S(P)) | ELISA | Mouse scFv |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1909-FY | Human Anti-SARS-CoV Recombinant Antibody (clone 03-001) | ELISA | Human IgG |
| HPAB-1910-FY | Human Anti-SARS-CoV Recombinant Antibody (clone 03-002) | ELISA | Human IgG |
| HPAB-1911-FY | Human Anti-SARS-CoV Recombinant Antibody (clone 03-009) | ELISA, IF, EM | Human IgG |
| HPAB-1912-FY | Human Anti-SARS-CoV Recombinant Antibody (clone 03-018) | ELISA, IF, EM, Inhib | Human IgG |
| HPAB-1913-FY | Human Anti-SARS-CoV Recombinant Antibody (clone G1) | ELISA, IF, IHC | Human IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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