This product is a mouse monoclonal antibody F26G6 targeting SARS-COV. F26G6 was generated by immunizing with inactivated SARS-CoV. F26G6 can be used in the development of diagnostic tools and passive treatments for SARS-CoV infection.
Figure 1 ELISA reactivity of mAbs with whole, inactivated SARS-CoV.
Hybridoma supernatants were tested at a 1:4 dilution in PBS+0.2% BSA on pre-blocked plates, coated with 18 ng per well of inactivated, highly purified SARS-CoV. Positive clones were identified as having positive binding (color) in wells that were at least four-fold higher than the background level reactivity on BSA. Antigen legend: black bars-native, highly purified SARS-CoV; white bars-heat denatured, highly purified SARS-CoV; grey bars-BSA control.
Berry, J. D., Jones, S., Drebot, M. A., Andonov, A., Sabara, M., Yuan, X. Y., ... & Plummer, F. (2004). Development and characterisation of neutralising monoclonal antibody to the SARS-coronavirus. Journal of virological methods, 120(1), 87-96.
Figure 2 Western immunoblot reactivity of mAbs with highly purified SARS-CoV.
The positive and preimmune control sera were from the corresponding immune mouse and tested at 1:2000 dilution in TBS+0.2% BSA. Lanes marked 1 were loaded with highly purified SARS-CoV, lanes marked 2 with infected Vero cell lysate.
Berry, J. D., Jones, S., Drebot, M. A., Andonov, A., Sabara, M., Yuan, X. Y., ... & Plummer, F. (2004). Development and characterisation of neutralising monoclonal antibody to the SARS-coronavirus. Journal of virological methods, 120(1), 87-96.
Figure 3 Competition ELISA measuring the binding of murine mAbs to highly purified SARS-CoV in the presence of human patient serum.
Dilutions (as indicated) of a normal human serum control (white bar), or serum from convalescent SARS patient S3 were applied to wells coated with highly purified whole SARS-CoV. mAb F26G6 (Spike specific; black bars) or F26G15 (nucleoprotein specific; grey bars) were then added to the reactions.
Berry, J. D., Jones, S., Drebot, M. A., Andonov, A., Sabara, M., Yuan, X. Y., ... & Plummer, F. (2004). Development and characterisation of neutralising monoclonal antibody to the SARS-coronavirus. Journal of virological methods, 120(1), 87-96.
Figure 4 Immunofluorescence staining of SARS-CoV-infected Vero cells with Western immunoblot negative, neutralising mAbs to SARS-CoV.
Berry, J. D., Jones, S., Drebot, M. A., Andonov, A., Sabara, M., Yuan, X. Y., ... & Plummer, F. (2004). Development and characterisation of neutralising monoclonal antibody to the SARS-coronavirus. Journal of virological methods, 120(1), 87-96.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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CAT | Product Name | Application | Type |
---|---|---|---|
MOB-885-S(P) | Recombinant Anti-SARS-CoV Antibody scFv Fragment | RIA, ELISA, FuncS | scFv |
MHH-885-S(P) | Recombinant Human Anti-SARS-CoV Antibody scFv Fragment | Neut, IF, FuncS | scFv |
HPAB-S0121-YC-S(P) | Mouse Anti-SARS-CoV Recombinant Antibody (clone F26G19); scFv Fragment | Neut | Mouse scFv |
HPAB-2048-FY-S(P) | Human Anti-SARS-CoV Recombinant Antibody (clone CR03-014); scFv Fragment | Neut, ELISA, FC | Human scFv |
HPAB-2049-FY-S(P) | Human Anti-SARS-CoV Recombinant Antibody (clone CR03-022); scFv Fragment | Neut, ELISA, FC | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
MRO-649LC | Mouse Anti-SARS-CoV Recombinant Antibody (MRO-649LC) | ELISA | Mouse antibody |
MRO-650LC | Mouse Anti-SARS-CoV Recombinant Antibody (MRO-650LC) | ELISA | Mouse antibody |
MRO-651LC | Mouse Anti-SARS-CoV Recombinant Antibody (MRO-651LC) | ELISA | Mouse antibody |
MRO-652LC | Mouse Anti-SARS-CoV Recombinant Antibody (MRO-652LC) | ELISA | Mouse antibody |
MRO-649LC-S(P) | Mouse Anti-SARS-CoV Recombinant Antibody; scFv Fragment (MRO-649LC-S(P)) | ELISA | Mouse scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0297CQ | Recombinant Human Anti-SARS-CoV Antibody (HuMAb 03-014) | ELISA, FC, Neut | Human IgG1 |
HPAB-0102LY | Recombinant Anti-SARS-CoV Antibody (S227.14) | ELISA, RIA, Inhib | |
HPAB-0103LY | Recombinant Anti-SARS-CoV Antibody (S230.15) | ELISA, RIA, Inhib | |
HPAB-0104LY | Recombinant Anti-SARS-CoV Antibody (S109.8) | ELISA, RIA, Inhib | |
HPAB-2049-FY | Human Anti-SARS-CoV Recombinant Antibody (clone CR03-022) | ELISA, FC | Human IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-1909-FY-S(P) | Human Anti-SARS-CoV Recombinant Antibody (clone 03-001); Fab Fragment | ELISA | Human Fab |
HPAB-1910-FY-S(P) | Human Anti-SARS-CoV Recombinant Antibody (clone 03-002); Fab Fragment | ELISA | Human Fab |
HPAB-1911-FY-S(P) | Human Anti-SARS-CoV Recombinant Antibody (clone 03-009); Fab Fragment | ELISA | Human Fab |
HPAB-1912-FY-S(P) | Human Anti-SARS-CoV Recombinant Antibody (clone 03-018); Fab Fragment | ELISA | Human Fab |
HPAB-1913-FY-S(P) | Human Anti-SARS-CoV Recombinant Antibody (clone G1); Fab Fragment | ELISA, IF, IHC | Humanized Fab |
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