Human Anti-SERPINF2 Recombinant Antibody (clone ch77A3) (CAT#: HPAB-A1330-YJ)
This product is a chimeric (mouse/human) antibody that recognizes SERPINF2.
Specific Inquiry
RIA
Figure 1 Competition binding assays of monoclonal antibodies 49C9, 70B11, 77A3, RWR and anti-digoxin with immobilized 70B11.
FuncS
Figure 2 The effect of monoclonal antibodies (mAbs) on plasma clot lysis by plasmin.
Sazonova, I. Y., Thomas, B. M., Gladysheva, I. P., Houng, A. K., & Reed, G. L. (2007). Fibrinolysis is amplified by converting α2‐antiplasmin from a plasmin inhibitor to a substrate. Journal of Thrombosis and Haemostasis, 5(10), 2087-2094.
Inhib
Figure 3 Influence of monoclonal antibodies (mAbs) on the inhibition of various serine proteases by a2-antiplasmin (a2-AP).
Sazonova, I. Y., Thomas, B. M., Gladysheva, I. P., Houng, A. K., & Reed, G. L. (2007). Fibrinolysis is amplified by converting α2‐antiplasmin from a plasmin inhibitor to a substrate. Journal of Thrombosis and Haemostasis, 5(10), 2087-2094.
ELISA
Figure 4 Results of murine 77A3, chimeric 77A3 and humanized 77A3-1 in the plasmin assay with chromogenic substrate.
IA
Figure 5 Binding of monoclonal antibodies (mAbs) to native a2-antiplasmin (a2-AP) in solution.
Sazonova, I. Y., Thomas, B. M., Gladysheva, I. P., Houng, A. K., & Reed, G. L. (2007). Fibrinolysis is amplified by converting α2‐antiplasmin from a plasmin inhibitor to a substrate. Journal of Thrombosis and Haemostasis, 5(10), 2087-2094.
IB
Figure 6 Immunoblotting experiments established the binding of mAbs 77 and 49 to various recombinant a2-APs.
Sazonova, I. Y., Thomas, B. M., Gladysheva, I. P., Houng, A. K., & Reed, G. L. (2007). Fibrinolysis is amplified by converting α2‐antiplasmin from a plasmin inhibitor to a substrate. Journal of Thrombosis and Haemostasis, 5(10), 2087-2094.
Specifications
- Host Species
- Human
- Derivation
- Chimeric (mouse/human)
- Type
- Chimeric (mouse/human) IgG1
- Specificity
- Human SERPINF2
- Species Reactivity
- Human
- Clone
- ch77A3
- Applications
- ELISA, Inhib, RIA, IB, IA, FuncS
Product Property
- Purification
- Protein A/G Purified
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the Certificate of Analysis for the lot-specific concentration.
- Buffer
- PBS
- Storage
- Store at 4°C for short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been reported for use in Enzyme-linked Immunosorbent Assay, Inhibition, Radioimmunoassay, Immunoblotting, Immunoassay, and Functional Assay. Optimal working dilutions must be determined by the end user.
Target
- Alternative Names
- AAP; API; PLI; A2AP; alpha2AP; ALPHA-2-PI; alpha-2-antiplasmin; alpha-2-AP; alpha-2-plasmin inhibitor; plasmin inhibitor; serine (or cysteine) proteinase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2; serpin F2; serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
- Gene ID
- 5345
- UniProt ID
- P08697
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "SERPINF2"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2109z | Mouse Anti-SERPINF2 Recombinant Antibody (clone 35A1) | WB, ELISA | Mouse IgG1 |
| MOB-0587MZ | Recombinant Mouse Anti-Human SERPINF2 Antibody (clone 820-2F-05) | ELISA, IHC-P, WB | Mouse antibody |
| HPAB-A1329-YJ | Mouse Anti-SERPINF2 Recombinant Antibody (clone 77A3) | ELISA, Inhib, RIA, IB, IA, FuncS | Mouse IgG |
| HPAB-A1331-YJ | Human Anti-SERPINF2 Recombinant Antibody (clone h77A3-1) | ELISA, Inhib, RIA, IB, IA, FuncS | Humanized IgG1 |
| HPAB-A1332-YJ | Human Anti-SERPINF2 Recombinant Antibody (clone h77A3-2) | ELISA, Inhib, RIA, IB, IA, FuncS | Humanized IgG1 |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1952CQ | Recombinant Mouse Anti-Serpinf2 Antibody (27C9) | ELISA, Inhib, WB | IgG |
| NEUT-1953CQ | Recombinant Mouse Anti-Serpinf2 Antibody (4H9) | ELISA, Inhib, WB | IgG1, κ |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-4216 | Hi-Affi™ Recombinant Rabbit Anti-SERPINF2 Monoclonal Antibody (SI295DS) | ELISA | IgG |
| MOR-4423 | Hi-Affi™ Recombinant Rabbit Anti-SerpinF2 Monoclonal Antibody (SI515DS) | WB, ELISA, IP | IgG |
| MOR-4424 | Hi-Affi™ Recombinant Rabbit Anti-SerpinF2 Monoclonal Antibody (SI516DS) | FC | IgG |
| MOR-4425 | Hi-Affi™ Recombinant Rabbit Anti-SerpinF2 Monoclonal Antibody (SI517DS) | FC | IgG |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for HPAB-A1330-YJ. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.