This product is a humanized antibody that recognizes SERPINF2.
Figure 1 Competition binding assays of monoclonal antibodies 49C9, 70B11, 77A3, RWR and anti-digoxin with immobilized 70B11.
Figure 2 The effect of monoclonal antibodies (mAbs) on plasma clot lysis by plasmin.
Sazonova, I. Y., Thomas, B. M., Gladysheva, I. P., Houng, A. K., & Reed, G. L. (2007). Fibrinolysis is amplified by converting α2‐antiplasmin from a plasmin inhibitor to a substrate. Journal of Thrombosis and Haemostasis, 5(10), 2087-2094.
Figure 3 Influence of monoclonal antibodies (mAbs) on the inhibition of various serine proteases by a2-antiplasmin (a2-AP).
Sazonova, I. Y., Thomas, B. M., Gladysheva, I. P., Houng, A. K., & Reed, G. L. (2007). Fibrinolysis is amplified by converting α2‐antiplasmin from a plasmin inhibitor to a substrate. Journal of Thrombosis and Haemostasis, 5(10), 2087-2094.
Figure 4 Results of murine 77A3, chimeric 77A3 and humanized 77A3-1 in the plasmin assay with chromogenic substrate.
Figure 5 Binding of monoclonal antibodies (mAbs) to native a2-antiplasmin (a2-AP) in solution.
Sazonova, I. Y., Thomas, B. M., Gladysheva, I. P., Houng, A. K., & Reed, G. L. (2007). Fibrinolysis is amplified by converting α2‐antiplasmin from a plasmin inhibitor to a substrate. Journal of Thrombosis and Haemostasis, 5(10), 2087-2094.
Figure 6 Immunoblotting experiments established the binding of mAbs 77 and 49 to various recombinant a2-APs.
Sazonova, I. Y., Thomas, B. M., Gladysheva, I. P., Houng, A. K., & Reed, G. L. (2007). Fibrinolysis is amplified by converting α2‐antiplasmin from a plasmin inhibitor to a substrate. Journal of Thrombosis and Haemostasis, 5(10), 2087-2094.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-2109z | Mouse Anti-SERPINF2 Recombinant Antibody (clone 35A1) | WB, ELISA | Mouse IgG1 |
MOB-0587MZ | Recombinant Mouse Anti-Human SERPINF2 Antibody (clone 820-2F-05) | ELISA, IHC-P, WB | Mouse antibody |
HPAB-A1329-YJ | Mouse Anti-SERPINF2 Recombinant Antibody (clone 77A3) | ELISA, Inhib, RIA, IB, IA, FuncS | Mouse IgG |
HPAB-A1330-YJ | Human Anti-SERPINF2 Recombinant Antibody (clone ch77A3) | ELISA, Inhib, RIA, IB, IA, FuncS | Chimeric (mouse/human) IgG1 |
HPAB-A1331-YJ | Human Anti-SERPINF2 Recombinant Antibody (clone h77A3-1) | ELISA, Inhib, RIA, IB, IA, FuncS | Humanized IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-1952CQ | Recombinant Mouse Anti-Serpinf2 Antibody (27C9) | ELISA, Inhib, WB | IgG |
NEUT-1953CQ | Recombinant Mouse Anti-Serpinf2 Antibody (4H9) | ELISA, Inhib, WB | IgG1, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-4216 | Hi-Affi™ Recombinant Rabbit Anti-SERPINF2 Monoclonal Antibody (SI295DS) | ELISA | IgG |
MOR-4423 | Hi-Affi™ Recombinant Rabbit Anti-SerpinF2 Monoclonal Antibody (SI515DS) | WB, ELISA, IP | IgG |
MOR-4424 | Hi-Affi™ Recombinant Rabbit Anti-SerpinF2 Monoclonal Antibody (SI516DS) | FC | IgG |
MOR-4425 | Hi-Affi™ Recombinant Rabbit Anti-SerpinF2 Monoclonal Antibody (SI517DS) | FC | IgG |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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