Mouse Anti-SLC3A2 Recombinant Antibody (clone B3) (CAT#: FAMAB-0168JF)
Recombinant monoclonal antibody clone B3 specially binds to human solute carrier family 3 member 2 (SLC3A2/CD98). This mouse anti-CD98 antibody (B3) can be widely used for the treatment studies of tumors, autoimmune disorders, and infectious diseases.
Specific Inquiry
FuncS
Figure 1 CD98hc-deficient epidermis is protected against tumor formation in vivo.
Number of papillomas per mouse is shown over the course of the experiment.
Estrach, S., Lee, S. A., Boulter, E., Pisano, S., Errante, A., Tissot, F. S., ... & Féral, C. C. (2014). CD98hc (SLC3A2) loss protects against ras-driven tumorigenesis by modulating integrin-mediated mechanotransduction. Cancer research, 74(23), 6878-6889.
IHC
Figure 2 CD98hc loss induces tumor regression.
Number of papillomas per mouse is shown over the course of the experiment.
Estrach, S., Lee, S. A., Boulter, E., Pisano, S., Errante, A., Tissot, F. S., ... & Féral, C. C. (2014). CD98hc (SLC3A2) loss protects against ras-driven tumorigenesis by modulating integrin-mediated mechanotransduction. Cancer research, 74(23), 6878-6889.
WB
Figure 3 Western blot analysis of FAK and Akt level of phosphorylation in CD98hc-deficient cells reconstituted with full-length human CD98hc (hCD98hc) or CD69 (control).
Total FAK, Akt, and a-tubulin are shown as controls.
Estrach, S., Lee, S. A., Boulter, E., Pisano, S., Errante, A., Tissot, F. S., ... & Féral, C. C. (2014). CD98hc (SLC3A2) loss protects against ras-driven tumorigenesis by modulating integrin-mediated mechanotransduction. Cancer research, 74(23), 6878-6889.
Specifications
- Immunogen
- Mimotope–KLH conjugates
- Host Species
- Mouse
- Derivation
- Mouse phage display Fab library
- Type
- Mouse IgG
- Specificity
- Human SLC3A2
- Species Reactivity
- Human
- Clone
- B3
- Applications
- WB, IHC, FuncS
- Related Disease
- Tumors
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The SLC3A2 antibody has been reported in applications of Western Blot, Immunohistochemistry, Functional Assay.
Target
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone B3"
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Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1096z | Mouse Anti-SLC3A2 Recombinant Antibody (clone 18C10) | FC, IF, FuncS | Mouse IgG1, κ |
| MOB-0528CT | Recombinant Mouse anti-Human SLC3A2 Monoclonal antibody (55E8) | FC, ICC/IF, IHC-Fr, IP | |
| HPAB-0123-CN | Mouse Anti-SLC3A2 Recombinant Antibody (HPAB-0123-CN) | ELISA, FC, IHC | Mouse IgG |
| FAMAB-0167JF | Mouse Anti-SLC3A2 Recombinant Antibody (clone A18) | WB, FC, IHC | Mouse IgG |
| FAMAB-0169JF | Mouse Anti-SLC3A2 Recombinant Antibody (clone C17) | WB, ELISA, IF, FC | Mouse IgG |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1974CQ | Recombinant Human Anti-SLC3A2 Antibody (HBJ127) | BL, Activation, ELISA, IF | IgG1, κ |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3303 | Hi-Affi™ Recombinant Rabbit Anti-SLC3A2 Monoclonal Antibody (DS3303AB) | IHC-P, IP, WB | IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0123-CN-S(P) | Mouse Anti-SLC3A2 Recombinant Antibody; scFv Fragment (HPAB-0123-CN-S(P)) | ELISA, FC, IHC | Mouse scFv |
| HPAB-0124-CN-S(P) | Mouse Anti-SLC3A2 Recombinant Antibody; scFv Fragment (HPAB-0124-CN-S(P)) | ELISA, FC, IHC | Mouse scFv |
| HPAB-0125-CN-S(P) | Human Anti-SLC3A2 Recombinant Antibody; scFv Fragment (HPAB-0125-CN-S(P)) | ELISA, FC, IHC | Human scFv |
| FAMAB-0169JF-S(P) | Mouse Anti-SLC3A2 Recombinant Antibody (clone C17); scFv Fragment | IF, ELISA, FuncS | Mouse scFv |
| PABJ-0174-S(P) | Mouse Anti-SLC3A2 Recombinant Antibody (clone MEM-108); scFv Fragment | ELISA | Mouse scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0123-CN-F(E) | Mouse Anti-SLC3A2 Recombinant Antibody; Fab Fragment (HPAB-0123-CN-F(E)) | ELISA, FC, IHC | Mouse Fab |
| HPAB-0124-CN-F(E) | Mouse Anti-SLC3A2 Recombinant Antibody; Fab Fragment (HPAB-0124-CN-F(E)) | ELISA, FC, IHC | Mouse Fab |
| FAMAB-0167JF-F(E) | Mouse Anti-SLC3A2 Recombinant Antibody (clone A18); Fab Fragment | IF, ELISA, FuncS | Mouse Fab |
| FAMAB-0168JF-F(E) | Mouse Anti-SLC3A2 Recombinant Antibody (clone B3); Fab Fragment | IF, ELISA, FuncS | Mouse Fab |
| PABJ-0174-F(E) | Mouse Anti-SLC3A2 Recombinant Antibody (clone MEM-108); Fab Fragment | ELISA | Mouse Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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