Human Anti-TROVE2 Recombinant Antibody (clone P1M49) (CAT#: FAMAB-0164JF)
Recombinant monoclonal antibody specially binds to TROVE domain family member 2 (TROVE2). This rabbit anti-TROVE2 antibody (P1M49) can be useful in the clinical diagnosis of patients with SLE.
Specific Inquiry
FC
Figure 1 The reactivity of antibody from LB32 was examined by antigen-binding beads assay.
The indicated proteins were coupled with streptavidin beads.
Takeshita, M., Suzuki, K., Kaneda, Y., Yamane, H., Ikeura, K., Sato, H., ... & Takeuchi, T. (2020). Antigen-driven selection of antibodies against SSA, SSB and the centromere ‘complex’, including a novel antigen, MIS12 complex, in human salivary glands. Annals of the rheumatic diseases, 79(1), 150-158.
IHC
Figure 2 An indirect fluorescent antibody test (ANA) of HEp-2 cells was performed using the antibody.
Scale bar indicates 20 µm.
Takeshita, M., Suzuki, K., Kaneda, Y., Yamane, H., Ikeura, K., Sato, H., ... & Takeuchi, T. (2020). Antigen-driven selection of antibodies against SSA, SSB and the centromere ‘complex’, including a novel antigen, MIS12 complex, in human salivary glands. Annals of the rheumatic diseases, 79(1), 150-158.
WB
Figure 3 Direct evidence of antigen-driven antibody selection against SSA and SSB.
Anti-GFP antibody was used as a positive control.
Takeshita, M., Suzuki, K., Kaneda, Y., Yamane, H., Ikeura, K., Sato, H., ... & Takeuchi, T. (2020). Antigen-driven selection of antibodies against SSA, SSB and the centromere ‘complex’, including a novel antigen, MIS12 complex, in human salivary glands. Annals of the rheumatic diseases, 79(1), 150-158.
ELISA
Figure 4 Monoclonal antibody TROVE2 reactivity to terminally truncated peptides analyzed by modified ELISA.
Resin without peptides was used
as a negative control.
Ødum Nielsen, I., Hartwig Trier, N., Friis, T., & Houen, G. (2016). Characterization of continuous monoclonal antibody epitopes in the N‐terminus of Ro60. Peptide Science, 106(1), 62-71.
Specifications
- Host Species
- Human
- Type
- Human IgM, λ
- Specificity
- Human TROVE2
- Species Reactivity
- Human
- Clone
- P1M49
- Applications
- WB, ELISA, IHC, FC
- Related Disease
- Systemic lupus erythematosus
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The C3 antibody has been reported in applications of Western Blot, Enzyme-linked Immunosorbent Assay, Immunohistochemistry, Flow Cytometry.
Target
- Alternative Names
- TROVE2; 60 KDa Ribonucleoprotein Ro; SSA2; RO60; Sjogren Syndrome Antigen A2 (60kDa, Ribonucleoprotein Autoantigen SS-A/Ro); Ro 60 KDa Autoantigen; SS-A; 60 KDa Ro Protein
- Gene ID
- 6738
- UniProt ID
- P10155
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1247z | Mouse Anti-TROVE2 Recombinant Antibody (clone 21C2) | ELISA, IHC, WB | Mouse IgG2a, κ |
| MOB-2110CT | Recombinant Mouse anti-Human TROVE2 Monoclonal antibody (EML2099) | WB | |
| FAMAB-0163JF | Human Anti-TROVE2 Recombinant Antibody (clone P1M398) | WB, IF, FC, FuncS | Human IgM, λ |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0163JF-F(E) | Human Anti-TROVE2 Recombinant Antibody (clone P1M398); Fab Fragment | IF, ELISA, FuncS | Human Fab |
| FAMAB-0164JF-F(E) | Human Anti-TROVE2 Recombinant Antibody (clone P1M49); Fab Fragment | IF, ELISA, FuncS | Human Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0163JF-S(P) | Human Anti-TROVE2 Recombinant Antibody (clone P1M398); scFv Fragment | IF, ELISA, FuncS | Human scFv |
| FAMAB-0164JF-S(P) | Human Anti-TROVE2 Recombinant Antibody (clone P1M49); scFv Fragment | IF, ELISA, FuncS | Human scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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