Recombinant Rabbit Anti-MADCAM1 Antibody (clone 12B5) (CAT#: VS4-CJ24)
This rabbit anti-MADCAM1 antibody (clone 12B5) is a product that recognizes human MADCAM1. The immunogen of this antibody is a synthesized peptide derived from human MADCAM1. The mAb has been tested for use in ELISA, Flow Cytometry (1:50-1:200).
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 IHC staining of human appendix
(Immunohistochemical staining of human appendix shows strong cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/77998/169642_A_3_2_selected.jpg
(Immunohistochemical staining of human appendix shows strong cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/77998/169642_A_3_2_selected.jpg
Figure 2 Appendix
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/75699/159464_A_2_2_val_selected.jpg
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/75699/159464_A_2_2_val_selected.jpg
Figure 3 Colon
(Endothelial cells Staining: High Intensity: Strong Quantity: 75%-25% Enterocytes -)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/75699/159464_A_8_3.jpg
(Endothelial cells Staining: High Intensity: Strong Quantity: 75%-25% Enterocytes -)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/75699/159464_A_8_3.jpg
Figure 4 Liver
(Hepatocytes Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/75699/159464_A_7_4.jpg
(Hepatocytes Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/75699/159464_A_7_4.jpg
Figure 5 Testis
(Cells in seminiferous ducts Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/75699/159464_A_6_6.jpg
(Cells in seminiferous ducts Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/75699/159464_A_6_6.jpg
Figure 6 RNA cell line category: Cell line enhanced (HEK93, Hep G2, U-266/70)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000099866-MADCAM1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000099866-MADCAM1
Specifications
- Immunogen
- A synthesized peptide derived from human MADCAM1
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human MADCAM1
- Species Reactivity
- Human
- Clone
- 12B5
- Applications
- ELISA, FC
- Conjugate
- Unconjugated
Product Property
- Purification
- Affinity chromatography
- Purity
- >95% as determined by SDS-PAGE
- Format
- Liquid
- Buffer
- 50% Glycerol, 150 mM NaCl, PBS, pH 7.4.
- Preservative
- 0.02% Sodium Azide
- Storage
- Store at -20°C or -80°C upon receipt. Avoid repeated freeze.
Applications
- Application Notes
- This antibody has been tested for use in ELISA, Flow Cytometry (1:50-1:200).
Target
- Alternative Names
- MACAM1
- Gene ID
- 8174
- UniProt ID
- Q13477
- Long Name
- Mucosal vascular addressin cell adhesion molecule 1
- Cellular Localization
- Membrane
- Post Translation Modifications
- The Ser/Thr-rich mucin-like domain may provide possible sites for O-glycosylation.
- Protein Refseq
- NP_570116.2; NP_570118.1
- Function
- Cell adhesion leukocyte receptor expressed by mucosal venules, helps to direct lymphocyte traffic into mucosal tissues including the Peyer patches and the intestinal lamina propria. It can bind both integrin alpha-4/beta-7 and L-selectin, regulating both the passage and retention of leukocytes. Isoform 2, lacking the mucin-like domain, may be specialized in supporting integrin alpha-4/beta-7-dependent adhesion strengthening, independent of L-selectin binding.
Recommended Products
Isotype Control
Secondary Antibody
Recommended Dilution Buffer
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "MADCAM1"
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1935z-F(E) | Recombinant Anti-Human MADCAM1 Antibody Fab Fragment | IF, Neut, FuncS | Fab |
| PFBL-635 | Mouse Anti-MADCAM1 Recombinant Antibody (clone 10G3); Fab Fragment | WB, IF, FuncS | Mouse Fab |
| PFBL-636 | Human Anti-MADCAM1 Recombinant Antibody (clone PF-547659); Fab Fragment | WB, IF, FuncS | Human Fab |
| HPAB-0040-DJB-F(E) | Human Anti-MADCAM1 Recombinant Antibody; Fab Fragment (HPAB-0040-DJB-F(E)) | ELISA | Human Fab |
| HPAB-692-FY-F(E) | Mouse Anti-MADCAM1 Recombinant Antibody; Fab Fragment (HPAB-692-FY-F(E)) | ELISA | Mouse Fab |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-509CL | Anti-Human MADCAM1 Recombinant Antibody (PF-00547659) | IHC, FuncS | Antibody |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-640 | Mouse Anti-MADCAM1 Recombinant Antibody (clone 10G3) | WB, IF, FuncS | Mouse IgG |
| MOB-1116CT | Recombinant Mouse anti-Human MADCAM1 Monoclonal antibody (28G6) | FC | |
| HPAB-0040-DJB | Human Anti-MADCAM1 Recombinant Antibody (HPAB-0040-DJB) | ELISA | Human IgG2, κ |
| HPAB-0041-DJB | Human Anti-MADCAM1 Recombinant Antibody (HPAB-0041-DJB) | ELISA | Human IgG4, κ |
| HPAB-0042-DJB | Human Anti-MADCAM1 Recombinant Antibody (HPAB-0042-DJB) | ELISA | Human IgG4, κ |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0714CL | Anti-Mouse Madcam1 Recombinant Antibody (MECA-367) | ELISA | |
| TAB-0714CL-S(P) | Anti-Mouse Madcam1 Recombinant Antibody scFv Fragment (MECA-367) | ELISA | |
| TAB-0714CL-F(E) | Anti-Mouse Madcam1 Recombinant Antibody Fab Fragment (MECA-367) | ELISA |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1715CQ | Recombinant Rat Anti-Madcam1 Antibody (11A55) | BL, WB | IgG2 |
| NEUT-1717CQ | Recombinant Mouse Anti-Madcam1 Antibody (CBL350) | BL, WB | IgG2a |
| NEUT-1718CQ | Recombinant Rat Anti-Madcam1 Antibody (MAB0842) | BL, FC, IHC-Fr, IP | IgG2 |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1716CQ | Recombinant Rat Anti-Madcam1 Antibody (CBL142) | Neut, WB | IgG2 |
| NEUT-1719CQ | Recombinant Rat Anti-Madcam1 Antibody (RM0284-11A55) | WB, Neut | IgG2 |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2118 | Hi-Affi™ Recombinant Rabbit Anti-MADCAM1 Monoclonal Antibody (DS2118AB) | WB | IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0040-DJB-S(P) | Human Anti-MADCAM1 Recombinant Antibody; scFv Fragment (HPAB-0040-DJB-S(P)) | ELISA | Human scFv |
| HPAB-0041-DJB-S(P) | Human Anti-MADCAM1 Recombinant Antibody; scFv Fragment (HPAB-0041-DJB-S(P)) | ELISA | Human scFv |
| HPAB-0042-DJB-S(P) | Human Anti-MADCAM1 Recombinant Antibody; scFv Fragment (HPAB-0042-DJB-S(P)) | ELISA | Human scFv |
| NS-051CN-S(P) | Human Anti-MADCAM1 Recombinant Antibody; scFv Fragment (NS-051CN-S(P)) | ELISA, WB, IHC, FC | Human scFv |
| HPAB-0178-FY-S(P) | Human Anti-MADCAM1 Recombinant Antibody (clone 7.16.6_S); scFv Fragment | FC | Human scFv |
Neuroscience Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NS-051CN | Human Anti-MADCAM1 Recombinant Antibody (NS-051CN) | ELISA, WB, IHC, FC, Block, FuncS | Human IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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