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IgE & FcγRII
The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene.
Immunoglobulin E is a type of antibody that has only been found in mammals. IgE is synthesised by plasma cells. Monomers of IgE consist of two heavy chains and two light chains, with the ε chain containing 4 Ig-like constant domains.
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- Targets: IgE & FcγRII
- Type: Fab2
- Application: FuncS, Promising therapeutic agent
- Rat Anti-IgE Recombinant Antibody (clone R1E4) (FAMAB-1380CQ)
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- Species Reactivity: Mouse
- Type: Rat IgG1
- Application: FC, FuncS, ELISA
- Mouse Anti-IgE Recombinant Antibody (clone mAbA9) (FAMAB-1877CQ)
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- Species Reactivity: Mouse
- Type: Mouse IgG1
- Application: Block, ELISA, FC
- Human Anti-IgE Recombinant Antibody (clone 2E19); scFv Fragment (HPAB-0126-FY-S(P))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scFv
- Application: FC
- Human Anti-IgE Recombinant Antibody (clone 2E19) (HPAB-0126-FY)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgE
- Application: FC, ELISA
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- Host Species: Human
- Specificity: Human
- Type: Human antibody
- Glycosylation site: aa73-75 of VH
aa301-303 of CH - Glycoform (ratio): G2
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- Host Species: Human
- Specificity: Human
- Type: Human antibody
- Glycosylation site: aa73-75 of VH
aa301-303 of CH - Glycoform (ratio): G2
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- Host Species: Human
- Specificity: Human
- Type: Humanized antibody
- Glycosylation site: Fc region
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- Host Species: Human
- Specificity: Human
- Type: Human antibody
- Glycosylation site: aa73-75 of VH
aa301-303 of CH - Glycoform (ratio): G1
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- Host Species: Human
- Specificity: Human
- Type: Humanized antibody
- Glycosylation site: Fc region
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- Host Species: Human
- Specificity: Human
- Type: Human antibody
- Glycosylation site: aa73-75 of VH
aa301-303 of CH - Glycoform (ratio): G1
- Anti-Human IgE Recombinant Antibody Fab Fragment (IGE026) (TAB-050ZJ-F(E))
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- Species Reactivity: Cynomolgus monkey, Human
- Type: Humanized antibody
- Application: ELISA, Inhib, FC
- Anti-Human IgE Recombinant Antibody (IGE026) (TAB-050ZJ)
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- Species Reactivity: Cynomolgus monkey, Human
- Type: Humanized antibody
- Application: ELISA, Inhib, FC
- Anti-Human IgE Recombinant Antibody scFv Fragment (IGE026) (TAB-050ZJ-S(P))
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- Species Reactivity: Cynomolgus monkey, Human
- Type: Humanized antibody
- Application: ELISA, Inhib, FC
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- Host Species: Human
- Specificity: Human
- Type: Human antibody
- Glycosylation site: aa73-75 of VH
aa301-303 of CH - Glycoform (ratio): G0
- Anti-Human IgE Recombinant Antibody (IGE009) (TAB-049ZJ)
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- Species Reactivity: Cynomolgus monkey, Human
- Type: Humanized antibody
- Application: ELISA, Inhib, FC
- Anti-Human IgE Recombinant Antibody Fab Fragment (IGE009) (TAB-049ZJ-F(E))
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- Species Reactivity: Cynomolgus monkey, Human
- Type: Humanized antibody
- Application: ELISA, Inhib, FC
- Anti-Human IgE Recombinant Antibody scFv Fragment (IGE009) (TAB-049ZJ-S(P))
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- Species Reactivity: Cynomolgus monkey, Human
- Type: Humanized antibody
- Application: ELISA, Inhib, FC
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- Host Species: Human
- Specificity: Human
- Type: Human antibody
- Glycosylation site: aa73-75 of VH
aa301-303 of CH - Glycoform (ratio): G0
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- Derivation: VHH phage library
- Species Reactivity: Cynomolgus monkey, Human
- Type: Single domain antibody
- Application: ELISA, Inhib, FC
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For Research Use Only. Not For Clinical Use.