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Anti-BaX Intrabody [+36GFP] (IAB-B001(G))

Recombinant anti-BaX intrabody in fusion with +36GFP works within cells to bind pro-apoptotic protein BaX, expressed in CHO cells. These intrabodies are useful drugs on their own as well as a means for identifying small compound drugs for degenerative diseases involving oxidative-stress-induced apoptosis.      

Specifications
Immunogen
human BCL2-associated X protein
Host
llama
Type
vhh-(+36GFP)
Cell Penetrating Peptide
+36 GFP
GFP with a theoretical net charge of +36 (+36 GFP) penetrated several different mammalian cell lines at very low (nanomolar) concentrations. Cationic peptides and proteins have been observed to penetrate cells, and both natural and synthetic cell-penetrating peptides are widely used as delivery vehicles. However, whereas a covalent link between the cell-penetrating peptide and its cargo is typically required.
Species Reactivity
human
Applications
Formats of immunological tests: Protein fragment complementation; Neutralization; Functional studies
Target
Alternative Names
BAX; BCL2-associated X protein; BCL2L4; apoptosis regulator BAX; bcl2-L-4; Baxdelta2G9; Baxdelta2omega; Baxdelta2G9omega
Entrez Gene ID
581
UniProt ID
Q07812

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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