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Rabbit Anti-HTT Recombinant Antibody (clone DS1714AB) (CAT#: MOR-1714)

Recombinant Rabbit anti-HTT monoclonal antibody for WB, IHC-P, ICC, excellent for producing superior results. Hi-Affi™ antibodies are developed from different sources, such as B cells of immunized animals, hybridoma, phage display library. The application of recombinant technology avoids the traditional ascitic fluid approach, which achieves the antibody generation in a humane way with much larger scale, greater specificity and sensitivity, and not susceptible to cell-line drift or lot-to-lot variation.


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Specific Inquiry
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  • Purity:
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  • Gene Expression
  • Datasheet
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  • COA
Subcellular Location and Protein Expression
Figure 1 IF staining of human cell line U-2 OS
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to nucleoplasm & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/26114/if_selected.jpg
Figure 2 IHC staining of human cerebral cortex
Figure 2 IHC staining of human cerebral cortex
(Immunohistochemical staining of human cerebral cortex shows strong cytoplasmic positivity in neuronal cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/26114/55354_B_9_5_selected.jpg
Figure 3 IF staining of human cell line A-431
Figure 3 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/26114/299_A6_2_red_green.jpg
Figure 4 IF staining of human cell line U-251 MG
Figure 4 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm & cytosol.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/26114/298_A6_1_red_green.jpg
Normal Tissue
Figure 5 Cerebral cortex
Figure 5 Cerebral cortex
(Neuronal cells
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Neuropil
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2756/7010_B_8_5.jpg
Figure 6 Colon
Figure 6 Colon
(Glandular cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2756/7010_A_7_3.jpg
Figure 7 Kidney
Figure 7 Kidney
(Cells in tubules
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2756/7010_A_9_5.jpg
Figure 8 Testis
Figure 8 Testis
(Cells in seminiferous ducts
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Leydig cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Nuclear)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2756/7010_A_4_6.jpg
Figure 9 Lymph node
Figure 9 Lymph node
(Non-germinal center cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2756/7010_A_8_8.jpg

Specifications

  • Immunogen
  • Synthetic peptide, corresponding to residues in the N terminus of Human Huntingtin.
  • Host Species
  • Rabbit
  • Derivation
  • Phage display library
  • Type
  • Rabbit IgG
  • Specificity
  • Human HTT
  • Species Reactivity
  • Human
  • Clone
  • DS1714AB
  • Applications
  • WB, IHC-P, ICC
  • Conjugate
  • Unconjugated

Product Property

  • Purification
  • Protein A purified
  • Purity
  • >95% as determined by SDS-PAGE
  • Format
  • Liquid
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • HD; IT15

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "HTT"

Single-domain Antibody

CAT Product Name Application Type
NAB-1905-VHH Recombinant Anti-human HTT VHH Single Domain Antibody IHC, ICC, FC, FA, FUNC Llama VHH
PABJ-0201 Human Anti-HTT Recombinant Antibody (PABJ-0201) ELISA, FuncS Human VL

Recombinant Antibody

CAT Product Name Application Type
MOB-521 Recombinant Anti-human HTT Antibody WB, Neut, FuncS IgG
MHH-521 Recombinant Human Anti-human HTT Antibody WB, Neut, FuncS IgG
PABL-580 Human Anti-HTT Recombinant Antibody (clone C4) Block Human IgG
PABL-581 Human Anti-HTT Recombinant Antibody (clone E51) FC, ELISA Human IgG
MRO-0801-CN Rabbit Anti-HTT Recombinant Antibody (clone JB89-34) WB, IHC, FC, IF Rabbit IgG

scFv Fragment Antibody

CAT Product Name Application Type
MOB-521-S(P) Recombinant Anti-human HTT Antibody scFv Fragment FC, Neut, Funcs scFv
MHH-521-S(P) Recombinant Human Anti-human HTT Antibody scFv Fragment ELISA, WB, FuncS scFv
PSBL-575 Human Anti-HTT Recombinant Antibody (clone C4); scFv Fragment Block Human scFv
PSBL-576 Human Anti-HTT Recombinant Antibody (clone E51); scFv Fragment FC, ELISA Human scFv
HPAB-0121-YC-S(P) Mouse Anti-HTT Recombinant Antibody (clone MW1); scFv Fragment ELISA, FC, WB, IHC Mouse scFv

Intrabody

CAT Product Name Application Type
IAB-B023(A) Recombinant Anti-human HTT Intrabody [(D-Arg)9] ELISA, WB, ICC, FuncS scFv-(D-Arg)9
IAB-B023(G) Recombinant Anti-human HTT Intrabody [+36 GFP] IF, FC, WB, FuncS scFv-(+36GFP)
IAB-B023(T) Recombinant Anti-human HTT Intrabody [Tat] WB, CO-IP, FuncS scFv-Tat

Fab Fragment Antibody

CAT Product Name Application Type
MHH-521-F(E) Recombinant Human Anti-human HTT Antibody Fab Fragment Neut, WB, FuncS Fab
PFBL-575 Human Anti-HTT Recombinant Antibody (clone C4); Fab Fragment Block Human Fab
PFBL-576 Human Anti-HTT Recombinant Antibody (clone E51); Fab Fragment FC, ELISA Human Fab
HPAB-0121-YC-F(E) Mouse Anti-HTT Recombinant Antibody (clone MW1); Fab Fragment ELISA, FC, WB, IHC Mouse Fab
HPAB-0122-YC-F(E) Mouse Anti-HTT Recombinant Antibody; Fab Fragment (HPAB-0122-YC-F(E)) ELISA, FC, WB, IHC Mouse Fab

Human Antibody

CAT Product Name Application Type
TAB-114CT Human Anti-HTT Recombinant Antibody (TAB-114CT) ELISA, WB Human IgG1, κ
TAB-114CT-S(P) Human Anti-HTT Recombinant Antibody; scFv Fragment (TAB-114CT-S(P)) ELISA, WB Human scFv
TAB-114CT-F(E) Human Anti-HTT Recombinant Antibody; Fab Fragment (TAB-114CT-F(E)) ELISA, WB Human Fab
PABX-109 Recombinant Human Anti-Huntingtin (Htt) Antibody WB, Neut, FuncS IgG
PABX-108-S (P) Recombinant Mouse Anti-Huntingtin (Htt) Antibody scFv Fragment (3B5H10) WB, ELISA, FuncS scFv

Mouse Antibody

CAT Product Name Application Type
TAB-115CT-S(P) Mouse Anti-HTT Recombinant Antibody; scFv Fragment (TAB-115CT-S(P)) ELISA, WB Mouse scFv
TAB-116CT-S(P) Mouse Anti-HTT Recombinant Antibody; scFv Fragment (TAB-116CT-S(P)) ELISA, WB Mouse scFv
TAB-117CT-S(P) Mouse Anti-HTT Recombinant Antibody; scFv Fragment (TAB-117CT-S(P)) ELISA, WB Mouse scFv
TAB-116CT-F(E) Mouse Anti-HTT Recombinant Antibody; Fab Fragment (TAB-116CT-F(E)) ELISA, WB Mouse Fab
TAB-117CT-F(E) Mouse Anti-HTT Recombinant Antibody; Fab Fragment (TAB-117CT-F(E)) ELISA, WB Mouse Fab

Neuroscience Antibody

CAT Product Name Application Type
NS-039CN Human Anti-HTT Recombinant Antibody (NS-039CN) ELISA, DB, IHC, FuncS Human IgG
NS-039CN-F(E) Human Anti-HTT Recombinant Antibody; Fab Fragment (NS-039CN-F(E)) ELISA Human Fab
NS-039CN-S(P) Human Anti-HTT Recombinant Antibody; scFv Fragment (NS-039CN-S(P)) ELISA Human scFv

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-0066-FY Rabbit Anti-HTT Recombinant Antibody (clone AFY0037) FC, ICC, IHC, WB Rabbit IgG

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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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