Recombinant Mouse anti-Human IL1R1 Monoclonal antibody (732229) (CAT#: MOB-0953CT)
Recombinant Mouse monoclonal antibody to Human IL1R1, expressed in Chinese Hamster Ovary cells(CHO).
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line ASC TERT1
(Immunofluorescent staining of human cell line ASC TERT1 shows localization to nucleoplasm, plasma membrane & cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1237/1774_H4_18_cr5952945990756_selected.jpg
(Immunofluorescent staining of human cell line ASC TERT1 shows localization to nucleoplasm, plasma membrane & cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1237/1774_H4_18_cr5952945990756_selected.jpg
Figure 2 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/7779/211_A1_3_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/7779/211_A1_3_selected.jpg
Figure 3 IHC staining of human small intestine
(Immunohistochemical staining of human small intestine shows strong luminal membranous positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/29560/ihc_selected.jpg
(Immunohistochemical staining of human small intestine shows strong luminal membranous positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/29560/ihc_selected.jpg
Figure 4 Testis
(Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5823/130948_A_6_6.jpg
(Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5823/130948_A_6_6.jpg
Figure 5 Lymph node
(Germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5823/130948_A_8_8.jpg
(Germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5823/130948_A_8_8.jpg
Figure 6 Cerebral cortex
(Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5823/130948_B_8_5.jpg
(Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5823/130948_B_8_5.jpg
Figure 7 Colon
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5823/130948_A_8_3.jpg
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5823/130948_A_8_3.jpg
Figure 8 Liver
(Hepatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5823/130948_A_9_4.jpg
(Hepatocytes Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/5823/130948_A_9_4.jpg
Figure 9 RNA cell line category: Cell line enhanced (ASC diff, ASC TERT1, HHSteC, HSkMC)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000115594-IL1R1
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000115594-IL1R1
Specifications
- Immunogen
- The extracellular domain of the type 1 human IL1 Receptor.
- Host Species
- Mouse
- Specificity
- This antibody partially inhibits (30-50%) binding of one another to IL1 Receptor. It does not block binding of IL1 to receptor and they do not cross react with receptors for human IL2 or IL4
- Species Reactivity
- Human
- Clone
- 732229
- Applications
- Used for immunoassay techniques such as: Enzyme-linked Immunosorbent Assay; Immunocytochemistry/Immunofluorescence; RIA
- Conjugate
- Unconjugated
Product Property
- Purity
- Protein G purified
- Format
- Liquid
- Concentration
- 1.1 mg/ml
- Buffer
- Preservative: None Constituents: PBS, pH 7.4
- Storage
- Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Target
- Alternative Names
- IL1R1; interleukin 1 receptor, type I; P80; IL1R; IL1RA; CD121A; D2S1473; IL-1R-alpha; interleukin-1 receptor type 1; IL-1R-1; IL-1RT1; IL-1RT-1; interleukin-1 receptor alpha; interleukin-1 receptor type I; CD121 antigen-like family member A; interleukin 1 receptor alpha, type I;
- Gene ID
- 3554
- UniProt ID
- P14778
- Protein Refseq
- NP_000868
- Function
- interleukin-1 receptor activity; interleukin-1, Type I, activating receptor activity; platelet-derived growth factor receptor binding; protease binding; protein binding; receptor activity; signal transducer activity; transmembrane signaling receptor activ
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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See other products for "IL1R1"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1421z | Mouse Anti-IL1R1 Recombinant Antibody (clone 32H6) | WB, ELISA, FC, ICC, IHC | Mouse IgG1 |
| HPAB-1862-FY | Human Anti-IL1R1 Recombinant Antibody (clone 26F5) | Inhib, Block | Human IgG1 |
| HPAB-1863-FY | Human Anti-IL1R1 Recombinant Antibody (clone 15C4) | Inhib, Block | Human IgG1 |
| VS3-QX596 | Mouse Anti-IL1R1 Recombinant Antibody (clone D12-D2) | WB, FC, ELISA | Mouse IgG1 |
| VS3-QX597 | Mouse Anti-IL1R1 Recombinant Antibody (clone 4D2D12) | ELISA, FC | Mouse IgG1 |
Immunotoxin
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-L026P | anti-IL1R1 immunotoxin TP3 (IgG)-PAP | Cytotoxicity assay, Functional assay |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-392CL | Afuco™ Anti-IL1R1 Recombinant Antibody (AFC-392CL), ADCC Enhanced | ELISA, WB | Human IgG1 |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-213CT | Human Anti-IL1R1 Recombinant Antibody (TAB-213CT) | ELISA, BL | Human IgG |
| TAB-214CT | Human Anti-IL1R1 Recombinant Antibody (TAB-214CT) | ELISA, BL | Human IgG |
| TAB-215CT | Anti-Human IL-1R1 (interleukin-1 receptor 1) Recombinant Antibody (6GL) | ELISA, BL | Human antibody |
| TAB-220CT | Human Anti-IL1R1 Recombinant Antibody (TAB-220CT) | ELISA, Inhibion, BL, IB | Human IgG |
| TAB-213CT-F(E) | Human Anti-IL1R1 Recombinant Antibody; Fab Fragment (TAB-213CT-F(E)) | ELISA, BL | Human Fab |
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-216CT | Anti-Human IL-1R1 (Interleukin 1 receptor type 1) Therapeutic Single Domain Antibody (DOM4-130) | Inhib | Single domain antibody |
| TAB-217CT | Anti-Human IL-1R1 (Interleukin 1 receptor type 1) Therapeutic Single Domain Antibody (D0M4-130-46) | ELISA | Single domain antibody |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1293CQ | Hamster Anti-Il1r1 Recombinant Antibody (clone JAMA147) | Neut | Hamster IgG |
| NEUT-1294CQ | Rat Anti-Il1r1 Recombinant Antibody (clone CBL936) | ELISA, IP, Neut, WB | Rat IgG1 |
| NEUT-1295CQ | Rat Anti-Il1r1 Recombinant Antibody (clone CBL937) | Neut, WB | Rat IgG1 |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1799 | Rabbit Anti-IL1R1 Recombinant Antibody (clone DS1799AB) | WB, FC, IP | Rabbit IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1862-FY-F(E) | Human Anti-IL1R1 Recombinant Antibody (clone 26F5); scFv Fragment | ELISA | Human scFv |
| HPAB-1863-FY-F(E) | Human Anti-IL1R1 Recombinant Antibody (clone 15C4); scFv Fragment | ELISA | Human scFv |
| HPAB-1864-FY-F(E) | Human Anti-IL1R1 Recombinant Antibody (clone 27F2); scFv Fragment | ELISA | Human scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1862-FY-S(P) | Human Anti-IL1R1 Recombinant Antibody (clone 26F5); Fab Fragment | ELISA | Human Fab |
| HPAB-1863-FY-S(P) | Human Anti-IL1R1 Recombinant Antibody (clone 15C4); Fab Fragment | ELISA | Human Fab |
| HPAB-1864-FY-S(P) | Human Anti-IL1R1 Recombinant Antibody (clone 27F2); Fab Fragment | ELISA | Human Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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