Recombinant Mouse Antibody (C179) is capable of binding to IAV HA, expressed in Chinese Hamster Ovary cells (CHO).
Figure 1 The ELISA results of top 12 phage clones with higher C179/BSA ELISA signal ratio from Ph.D.-7, Ph.D.-12 and Ph.D.-C7C peptide phage-display libraries.
a: Phage clones from Ph.D.-7 peptide phage-display library. b: Phage clones from Ph.D.-12 peptide phage-display library; c: Phage clones from Ph.D.-C7C peptide phage-display library.
Zhong, Y., Cai, J., Zhang, C., Xing, X., Qin, E., He, J.,... & Song, H. (2011). Mimotopes selected with neutralizing antibodies against multiple subtypes of influenza A. Virology journal, 8(1), 542.
Figure 2 The in vitro binding activities of recombinant multi-mimotope.
Zhong, Y., Cai, J., Zhang, C., Xing, X., Qin, E., He, J.,... & Song, H. (2011). Mimotopes selected with neutralizing antibodies against multiple subtypes of influenza A. Virology journal, 8(1), 542.
Figure 3 Evaluation of ELISA. Group 1 HA stalk antigen coated onto the wells of an ELISA plate maintained important conformational epitopes.
(A to C) ELISA binding of group 1 HA stalk-binding monoclonal antibodies (in picograms per 50 μl) was measured using serial dilutions of monoclonal antibodies CR6261 (A), C179 (B), and 70-1F02 (C). (D) H1 HA globular head-binding monoclonal antibody EM4CO4 was used as a negative control. Anti-HA stalk serum titers measured from patient samples in this study showed strong positive correlation with the level of inhibition to potent group 1 HA stalk-binding monoclonal antibodies. Samples were ranked by the anti-HA stalk antibody titer and the percent inhibition to stalk-binding monoclonal antibodies for Spearman's rank correlation analysis. (E to G) Increasing anti-HA stalk titer showed a strong and significant tendency of increasing inhibition of CR6261 (E), C179 (F), and 70-1F02 (G) binding.
Park, J. K., Han, A., Czajkowski, L., Reed, S., Athota, R., Bristol, T.,... & Memoli, M. J. (2018). Evaluation of preexisting anti-hemagglutinin stalk antibody as a correlate of protection in a healthy volunteer challenge with influenza A/H1N1pdm virus.MBio, 9(1), e02284-17.
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• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
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CAT | Product Name | Application | Type |
---|---|---|---|
PABZ-184 | Recombinant Human Anti-H1N1 HA Antibody (UCA) | WB, ELISA | IgG |
PABZ-186 | Recombinant Human Anti-H2N2 HA Antibody (2G1) | Neut | IgG |
PABZ-195 | Recombinant Mouse Anti-H3N2 HA Antibody (S139/1) | Neut | IgG |
PABZ-198 | Recombinant Human Anti-H3N2 HA Antibody (C05) | Neut | IgG |
FAMAB-0254YC | Recombinant Mouse Anti-HA Antibody (H153-70A12) | ELISA | Mouse IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
PFBZ-076 | Recombinant Mouse Anti-IAV HA1 Antibody Fab Fragment (26/9) | ELISA | IgG |
PFBC-078 | Recombinant Mouse Anti-IAV HA (T131I) Antibody Fab Fragment | Neut | IgG |
PFBZ-078 | Recombinant Mouse Anti-IAV HA heptapeptide (DVPDYAS) Antibody Fab Fragment (17/9) | ELISA | IgG |
PFBL-479 | Recombinant Human Anti-H1N1 HA Antibody Fab Fragment (CH65) | WB, ELISA, FuncS | Fab |
PFBL-480 | Recombinant Human Anti-H1N1 HA Antibody Fab Fragment (CH67) | Neut | Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
PFBC-160 | Human Anti-HA Recombinant Antibody; Fab Fragment (PFBC-160) | Neut, ELISA, FC | Human Fab |
PFBC-233 | Recombinant Human Anti-H3N2 HA Antibody Fab Fragment (F045-092) | Neut | Fab |
HPAB-0373-YJ-S(P) | Mouse Anti-HA Recombinant Antibody; scFv Fragment (HPAB-0373-YJ-S(P)) | ELISA, Neut, IF, FuncS | Mouse scFv |
HPAB-0928WJ-S(P) | Recombinant Mouse Anti-HA Antibody scFv Fragment (3C8) | ELISA | Mouse scFv |
HPAB-0929WJ-S(P) | Recombinant Mouse Anti-HA Antibody scFv Fragment (10F7) | ELISA | Mouse scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
MRO-265CT-F(E) | Anti-IAV HA Recombinant Antibody Fab Fragment (D4-4) | WB, FC, IP | Human antibody |
MRO-266CT-F(E) | Anti-IAV HA Recombinant Antibody Fab Fragment (D4-5) | WB, FC, IP | Human antibody |
MRO-267CT-F(E) | Anti-IAV HA Recombinant Antibody Fab Fragment (D5-3) | WB, FC, IP | Human antibody |
MRO-268CT-F(E) | Anti-IAV HA Recombinant Antibody Fab Fragment (D6-1) | WB, FC, IP | Human antibody |
PABX-069-S (P) | Recombinant Mouse Anti-Hemagglutinin (HA) Antibody scFv Fragment (S139/1) | ELISA, Neut, FuncS | scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
MRO-308CT-F(E) | Anti-IAV HA Recombinant Antibody Fab Fragment (8153) | WB, ELISA | |
MRO-309CT-F(E) | Anti-IAV HA Recombinant Antibody Fab Fragment (H36-7) | WB, ELISA | |
MRO-310CT-F(E) | Anti-IAV HA Recombinant Antibody Fab Fragment (H36-5) | WB, ELISA | |
MRO-311CT-F(E) | Anti-IAV HA Recombinant Antibody Fab Fragment (H36-17) | WB, ELISA | |
MRO-312CT-F(E) | Anti-IAV HA Recombinant Antibody Fab Fragment (H36-4) | WB, ELISA |
CAT | Product Name | Application | Type |
---|---|---|---|
PABX-070-S (P) | Recombinant Mouse Anti-HA1 Antibody scFv Fragment (Fab17/9) | WB, ELISA, Neut, FuncS | scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-4209 | Hi-Affi™ Recombinant Rabbit Anti-HA Monoclonal Antibody (SI287DS) | ELISA, ICC/IF, IF, FC | IgG |
MOR-4210 | Hi-Affi™ Recombinant Rabbit Anti-HA Monoclonal Antibody (SI288DS) | ELISA, ICC/IF, IF, FC | IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-1169-FY | Llama Anti-HA Recombinant Single Domain Antibody (HPAB-1169-FY) | Neut | Llama VHH |
HPAB-1170-FY | Llama Anti-HA Recombinant Single Domain Antibody (HPAB-1170-FY) | Neut | Llama VHH |
HPAB-1171-FY | Llama Anti-HA Recombinant Single Domain Antibody (HPAB-1171-FY) | Neut | Llama VHH |
HPAB-1172-FY | Llama Anti-HA Recombinant Single Domain Antibody (HPAB-1172-FY) | Neut | Llama VHH |
HPAB-1173-FY | Llama Anti-HA Recombinant Single Domain Antibody (HPAB-1173-FY) | Neut | Llama VHH |
CAT | Product Name | Application | Type |
---|---|---|---|
MHC-YF182 | DRB1*01:01/Influenza HA (PKYVKQNTLKLAT) MHC Monomer | MHC Multimer | |
MHC-YF183 | DRB1*04:01/Influenza HA (PKYVKQNTLKLAT) MHC Monomer | MHC Multimer | |
MHC-YF890 | DRB1*04:02/Human HA (PKYVKQNTLKLAT) MHC Tetramer | FCM | |
MHC-YF891 | DRB1*07:01/Human HA (PKYVKQNTLKLAT) MHC Tetramer | FCM | |
MHC-YF1498 | BV421-DRB1*04:02/Human HA (PKYVKQNTLKLAT) MHC Tetramer | FCM |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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