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Anti-LRP6 Fab (51213.2) (TAB-0108CL-F(E))

Anti-LRP6 antibodies can bind LRP6 epitopes with high affinity and then enhance Wnt signaling and/or antagonize Dkk1 activity which is related with the treatment of a variety of diseases, such as bone diseases, wound healing and gastrointestinal diseases.      

Specifications
Immunogen
Extracellular domain of LRP6
Host
Mouse
Specificity
Human
Species Reactivity
Cross-react with mouse LRP6
Clone
51213.2
Related Disease
Osteoporosis, rheumatoid arthritis, osteolytic lesions caused by osteoarthritis and multiple myeloma, gas-trointestinal disease and wound healing, radiation- or chemotherapy-induced mucositis
Target
Alternative Names
LRP6; low density lipoprotein receptor-related protein 6; ADCAD2; low-density lipoprotein receptor-related protein 6; LRP-6
Entrez Gene ID
4040
UniProt ID
O75581

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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