Recombinant Mouse Antibody (YADS1) is capable of binding to hVEGF, expressed in Chinese Hamster Ovary cells (CHO).
Figure 1 Antagonism of the hVEGF:Flt-1 interaction by anti-VEGF Fabs.
(a) Competitive ELISA measuring inhibition of hVEGF binding to immobilized Flt-1D2 by serial dilutions of Fab-YADS1 (open circles, IC50Z6(G 1) nM) or Fab-YADS2 (filled squares, IC50Z15(G10) nM). (b) Inhibition of hVEGF-stimulated HUVEC growth by serial diutions of Fab-YADS2 (filled squares). Fab-YADS2 did not inhibit HUVEC growth stimulated by basic fibroblast growth factor (open square).
Fellouse, F. A. , Barthelemy, P. A. , Kelley, R. F. , & Sidhu, S. S. . (2006). Tyrosine plays a dominant functional role in the paratope of a synthetic antibody derived from a four amino acid code. Journal of Molecular Biology, 357(1), 0-114.
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CAT | Product Name | Application | Type |
---|---|---|---|
TAB-H73 | Anti-Human VEGFA Recombinant Antibody (Vanucizumab) | WB, FC, IP, ELISA, Neut, FuncS, IF | VH - C-kappa - CH2 - CH3 _ V-lambda - CH1 _ H-GAMMA-1 _ L-kappa |
TAB-011 | Anti-Human VEGF Recombinant Antibody (Bevacizumab) | FC, IP, ELISA, Neut, FuncS, IF, ICC | IgG1 - kappa |
TAB-012-F(E) | Anti-Human VEGF Recombinant Antibody Fab Fragment (Ranibizumab) | IP, IF, FuncS, FC, Neut, ELISA, IHC | Fab - G1 - kappa |
TAB-307CQ | Human Anti-VEGFA Recombinant Antibody (TAB-307CQ) | Inhib | Human IgG |
TAB-307CQ-S(P) | Human Anti-VEGFA Recombinant Antibody; scFv Fragment (TAB-307CQ-S(P)) | ELISA, Neut | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
AGTO-L043L | anti-VEGFA immunotoxin Ng76 (scFv)-Luffin-β | Cytotoxicity assay, Functional assay |
CAT | Product Name | Application | Type |
---|---|---|---|
PFBW-075 | Mouse Anti-VEGFA Recombinant Antibody (clone YADS1); Fab Fragment | ELISA | Mouse Fab |
PFBC-076 | Mouse Anti-VEGFA Recombinant Antibody (clone YADS2); Fab Fragment | ELISA | Mouse Fab |
HPAB-M0372-YC-F(E) | Canine Anti-VEGFA Recombinant Antibody; Fab Fragment (HPAB-M0372-YC-F(E)) | ELISA, Inhib, FuncS | Chimeric (Mouse/Canine) Fab |
HPAB-M0373-YC-F(E) | Canine Anti-VEGFA Recombinant Antibody; Fab Fragment (HPAB-M0373-YC-F(E)) | ELISA, Inhib, FuncS | Chimeric (Mouse/Canine) Fab |
HPAB-M0374-YC-F(E) | Canine Anti-VEGFA Recombinant Antibody; Fab Fragment (HPAB-M0374-YC-F(E)) | ELISA, Inhib, FuncS | Chimeric (Mouse/Canine) Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-306CQ | Mouse Anti-VEGFA Recombinant Antibody (TAB-306CQ) | FuncS, Inhib | Mouse IgG |
TAB-306CQ-S(P) | Mouse Anti-VEGFA Recombinant Antibody; scFv Fragment (TAB-306CQ-S(P)) | ELISA, Neut | Mouse scFv |
TAB-306CQ-F(E) | Mouse Anti-VEGFA Recombinant Antibody; Fab Fragment (TAB-306CQ-F(E)) | ELISA, Neut | Mouse Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-284CQ-S(P) | Human Anti-VEGFA Recombinant Antibody; scFv Fragment (TAB-284CQ-S(P)) | ELISA | Human scFv |
TAB-304CQ-S(P) | Anti-Human VEGFA Recombinant Antibody scFv Fragment (2H1) | ELISA, WB | Human antibody |
TAB-284CQ-F(E) | Human Anti-VEGFA Recombinant Antibody; Fab Fragment (TAB-284CQ-F(E)) | ELISA | Human Fab |
TAB-304CQ-F(E) | Anti-Human VEGFA Recombinant Antibody Fab Fragment (2H1) | ELISA, WB | Human antibody |
TAB-305CQ-F(E) | Anti-Human VEGFA Recombinant Antibody Fab Fragment (2H1-32) | ELISA, WB | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
BRD-0623MZ | Chicken Anti-VEGF Polyclonal IgY | WB | Chicken antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-2255CQ | Mouse Anti-VEGFA Recombinant Antibody (clone CBL198) | Neut, WB | Mouse IgG1 |
NEUT-2256CQ | Rat Anti-Vegfa Recombinant Antibody (clone 2G11-2A05) | WB, Neut, ELISA, IHC, FuncS | Rat IgG2a, κ |
NEUT-2257CQ | Mouse Anti-VEGFA Recombinant Antibody (clone 16F1) | WB, Neut | Mouse IgG2a |
NEUT-2258CQ | Mouse Anti-VEGFA Recombinant Antibody (clone 4B2-8) | ELISA, Neut, WB | Mouse IgG1, κ |
NEUT-2260CQ | Mouse Anti-VEGFA Recombinant Antibody (clone CBL737) | WB, ELISA, Neut | Mouse IgG2b |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-2259CQ | Mouse Anti-VEGFA Recombinant Antibody (clone A.4.6.1) | ELISA, IP, WB, Block, FC, IHC | Mouse IgG1, κ |
NEUT-2267CQ | Mouse Anti-VEGFA Recombinant Antibody (clone A15136B) | WB, Block | Mouse IgG2b, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-3835 | Rabbit Anti-VEGFA Recombinant Antibody (clone DS3835AB) | FC, ICC, IF, IHC-P, IP, WB | Rabbit IgG |
MOR-4758 | Rabbit Anti-Vegfa Recombinant Antibody (clone TH272DS) | WB | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
FAMAB-0331-CN-VHH | Camelid Anti-VEGFA Recombinant Single Domain Antibody (clone VA12) | WB, ELISA | Camelid VHH |
HPAB-0671-CN | Human Anti-VEGFA Recombinant Antibody (HPAB-0671-CN) | ELISA, Neut | Humanized IgG |
HPAB-0336-YJ | Human Anti-VEGFA Recombinant Antibody (clone BAT-1706) | FuncS | Humanized IgG1 |
HPAB-0715-FY | Mouse Anti-VEGFA Recombinant Antibody (clone AB014) | ELISA, Inhib, IF | Mouse IgG |
HPAB-0950-FY | Camelid Anti-VEGFA Recombinant Antibody (HPAB-0950-FY) | Inhib | Camelid IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-TAB-465CQ | Afuco™ Anti-VEGFA ADCC Recombinant Antibody (Varisacumab), ADCC Enhanced | ELISA, IHC, FC, IP, IF, FuncS | ADCC enhanced antibody |
AFC-TAB-011 | Afuco™ Anti-VEGFA ADCC Recombinant Antibody (Bevacizumab), ADCC Enhanced | FC, IP, ELISA, Neut, FuncS, IF | ADCC enhanced antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-M0372-YC-S(P) | Canine Anti-VEGFA Recombinant Antibody; scFv Fragment (HPAB-M0372-YC-S(P)) | ELISA, Inhib, FuncS | Mouse scFv |
HPAB-0938WJ-S(P) | Human Anti-VEGFA Recombinant Antibody; scFv Fragment (HPAB-0938WJ-S(P)) | ELISA | Human scFv |
HPAB-1245WJ-S(P) | Human Anti-VEGFA Recombinant Antibody (clone AM2); scFv Fragment | ELISA | Human scFv |
HPAB-2046-FY-S(P) | Human Anti-VEGFA Recombinant Antibody (clone C1039); scFv Fragment | IA | Human scFv |
HPAB-0677YY-S(P) | Mouse Anti-VEGFA Recombinant Antibody (clone CBV110YJ); scFv Fragment | ELISA, FuncS | Mouse scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0337-YJ-vNAR | Recombinant Shark Anti-VEGFA vNAR (HPAB-0337-YJ-vNAR) | FC, ELISA, Inhib, Neut | Shark vNAR |
HPAB-0338-YJ-vNAR | Recombinant Shark Anti-VEGFA vNAR (HPAB-0338-YJ-vNAR) | FC, ELISA, Inhib, Neut | Shark vNAR |
HPAB-0646-YJ-VHH | Camelid Anti-VEGFA Recombinant Single Domain Antibody (HPAB-0646-YJ-VHH) | ELISA, Inhib | Camelid VHH |
HPAB-0647-YJ-VHH | Camelid Anti-VEGFA Recombinant Single Domain Antibody (HPAB-0647-YJ-VHH) | ELISA, Inhib | Camelid VHH |
HPAB-0648-YJ-VHH | Camelid Anti-VEGFA Recombinant Single Domain Antibody (HPAB-0648-YJ-VHH) | ELISA, Inhib | Camelid VHH |
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