Afuco™ Anti-F3 ADCC Recombinant Antibody (Tisotumab), ADCC Enhanced (CAT#: AFC-TAB-473CQ)
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to F3. tisotumab is a human monoclonal antibody that can be potentially used in the treatment of Solid tumors.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/49292/if_selected.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/49292/if_selected.jpg
Figure 2 IF staining of human cell line HaCaT
(Immunofluorescent staining of human cell line HaCaT shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/69132/1343_C8_1_selected.jpg
(Immunofluorescent staining of human cell line HaCaT shows localization to vesicles.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/69132/1343_C8_1_selected.jpg
Figure 3 IHC staining of human nasopharynx
(Immunohistochemical staining of human nasopharynx shows strong cytoplasmic positivity in respiratory epithelial cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9438/ihc_selected.jpg
(Immunohistochemical staining of human nasopharynx shows strong cytoplasmic positivity in respiratory epithelial cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9438/ihc_selected.jpg
Figure 4 Cerebral cortex
(Neuropil
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9438/27291_B_7_5.jpg
(Neuropil
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9438/27291_B_7_5.jpg
Figure 5 Testis
(Leydig cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9438/27291_A_6_6.jpg
(Leydig cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9438/27291_A_6_6.jpg
Figure 6 Placenta
(Decidual cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9438/27291_A_2_7.jpg
(Decidual cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/9438/27291_A_2_7.jpg
Figure 7 RNA cell line category: Cell line enhanced (A-431, HaCaT, HBEC3-KT, U-2197)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000117525-F3
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000117525-F3
Figure 7 RNA cell line category: Cell line enhanced (A-431, HaCaT, HBEC3-KT, U-2197)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000117525-F3
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000117525-F3
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Human
- Derivation
- Human
- Type
- ADCC enhanced antibody
- Specificity
- Human F3
- Species Reactivity
- Human
- Clone
- Tisotumab
- Applications
- ELISA, IHC, FC, IP, IF, Inhib
- Conjugate
- Unconjugated
- Generic Name
- Tisotumab
- Related Disease
- Solid tumors
Product Property
- Purity
- >95% by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- F3; coagulation factor III (thromboplastin, tissue factor); TF; TFA; CD142; tissue factor;
- Gene ID
- 2152
- UniProt ID
- P13726
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Tisotumab"
Anti-Human F3 Recombinant Antibody (Tisotumab)Recombinant monoclonal antibody to F3. tisotumab is a human monoclonal antibody that can be potentially used in the treatment of Solid tumors.
See other products for "F3"
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-258CL | Human Anti-F3 Recombinant Antibody (TAB-258CL) | ELISA | Human IgG |
| TAB-276CQ-S(P) | Human Anti-F3 Recombinant Antibody; scFv Fragment (TAB-276CQ-S(P)) | ELISA, FC | Humanized scFv |
| TAB-278CQ-S(P) | Human Anti-F3 Recombinant Antibody; scFv Fragment (TAB-278CQ-S(P)) | ELISA, FC | Humanized scFv |
| PABX-180 | Recombinant Human Anti-TF Antibody (D3H44) | WB, ELISA, FuncS | IgG |
| PABX-180-F (E) | Recombinant Human Anti-TF Antibody Fab Fragment (D3H44) | WB, ELISA, FuncS | Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBZ-043 | Mouse Anti-F3 Recombinant Antibody (clone 5G9); scFv Fragment | Block | Mouse scFv |
| PSBW-043 | Human Anti-F3 Recombinant Antibody (clone D3H44); scFv Fragment | WB, IHC, IF, FuncS | Humanized scFv |
| PSBL-468 | Human Anti-F3 Recombinant Antibody (clone 10H10); scFv Fragment | WB, IF, FuncS | Human scFv |
| HPAB-0113-YC-S(P) | Human Anti-F3 Recombinant Antibody; scFv Fragment (HPAB-0113-YC-S(P)) | ELISA, FC, Neut | Human scFv |
| HPAB-0114-YC-S(P) | Mouse Anti-F3 Recombinant Antibody; scFv Fragment (HPAB-0114-YC-S(P)) | ELISA | Mouse scFv |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-277CQ-S(P) | Mouse Anti-F3 Recombinant Antibody; scFv Fragment (TAB-277CQ-S(P)) | ELISA, FC | Mouse scFv |
| TAB-277CQ-F(E) | Mouse Anti-F3 Recombinant Antibody; Fab Fragment (TAB-277CQ-F(E)) | ELISA, FC | Mouse Fab |
| PABX-177-S (P) | Recombinant Human Anti-TF Antibody scFv Fragment (D3h44) | WB, ELISA, Neut, FuncS | scFv |
| PABX-179-S (P) | Recombinant Mouse Anti-TF Antibody scFv Fragment (D3) | WB, ELISA, IF, FuncS | scFv |
| PABX-179-F (E) | Recombinant Mouse Anti-TF Antibody Fab Fragment (D3) | WB, ELISA, IF, FuncS | Fab |
Deglycosylated Antibody (Non-glycosylated IgGs)
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-178LC | Recombinant Anti-Human F3 Antibody (Non-glycosylated) | ELISA | Human antibody |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1226 | Hi-Affi™ Rabbit Anti-F3 Recombinant Antibody (clone DS1226AB) | WB, IHC-P, ICC, IF | Rabbit IgG |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-473CQ | Anti-Human F3 Recombinant Antibody (Tisotumab) | ELISA, IHC, FC, IP, IF, Inhib | IgG1, κ |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0113-YC-F(E) | Human Anti-F3 Recombinant Antibody; Fab Fragment (HPAB-0113-YC-F(E)) | ELISA, FC, Neut | Human Fab |
| HPAB-0172CQ-F(E) | Human Anti-F3 Recombinant Antibody; Fab Fragment (HPAB-0172CQ-F(E)) | ELISA, FC | Chimeric (mouse/human) Fab |
| HPAB-0173CQ-F(E) | Human Anti-F3 Recombinant Antibody; Fab Fragment (HPAB-0173CQ-F(E)) | ELISA, FC | Chimeric (mouse/human) Fab |
| HPAB-0174CQ-F(E) | Human Anti-F3 Recombinant Antibody; Fab Fragment (HPAB-0174CQ-F(E)) | ELISA, FC | Chimeric (mouse/human) Fab |
| HPAB-0175CQ-F(E) | Human Anti-F3 Recombinant Antibody; Fab Fragment (HPAB-0175CQ-F(E)) | ELISA, WB, Inhib | Humanized Fab |
Epitope-Specific Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| EPAF-0573CQ | Mouse Anti-F3 Recombinant Antibody (clone hATR-5) | ELISA, Inhib | Mouse IgG4 |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0172CQ | Human Anti-F3 Recombinant Antibody (HPAB-0172CQ) | ELISA, FC, ADCC | Chimeric (mouse/human) IgG1 |
| HPAB-0173CQ | Human Anti-F3 Recombinant Antibody (HPAB-0173CQ) | ELISA, FC, ADCC | Chimeric (mouse/human) IgG1, λ |
| HPAB-0174CQ | Human Anti-F3 Recombinant Antibody (HPAB-0174CQ) | ELISA, FC, ADCC | Chimeric (mouse/human) IgG1, λ |
| HPAB-0175CQ | Human Anti-F3 Recombinant Antibody (HPAB-0175CQ) | ELISA, WB, Inhib | Humanized IgG1, κ |
| FN-224CQ | Mouse Anti-F3 Recombinant Antibody (clone HTF-1) | FC, FuncS, ICC, IF, WB | Mouse IgG1, κ |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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