Afuco™ Anti-FCER2 ADCC Recombinant Antibody (Gomiliximab), ADCC Enhanced (CAT#: AFC-TAB-231)
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to CD23. Gomiliximab is a monoclonal antibody acting as an immunosuppressive drug for the treatment of allergic asthma. It targets the low affinity IgE receptor (FcεRII or CD23). The drug is a chimeric antibody from Macaca irus and Homo sapiens.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 High expression in lymph node
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/8928/24032_A_9_8_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/8928/24032_A_9_8_val_selected.jpg
Figure 2 Low expression in endometrium 1
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/8928/24032_B_4_3_val_selected.jpg
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/8928/24032_B_4_3_val_selected.jpg
Figure 3 Bone marrow
(Hematopoietic cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2624/6435_B_5_4.jpg
(Hematopoietic cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2624/6435_B_5_4.jpg
Figure 4 Lymph node
(Germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2624/6435_A_9_8.jpg
(Germinal center cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/2624/6435_A_9_8.jpg
Figure 5 RNA cell line category: Cell line enriched (HDLM-2)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000104921-FCER2
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000104921-FCER2
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Primate
- Derivation
- Chimeric (primate/human)
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Clone
- Gomiliximab
- Applications
- Neut, ELISA, IF, IP, FuncS
- Conjugate
- Unconjugated
- Generic Name
- Gomiliximab
Product Property
- Purity
- >95% by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Gomiliximab; 357613-86-6; FCER2; Fc fragment of IgE, low affinity II, receptor for (CD23); CD23A, Fc fragment of IgE, low affinity II, receptor for (CD23A), FCE2; low affinity immunoglobulin epsilon Fc receptor; CD23; CLEC4J; BLAST-2; CD23 antigen; fc-epsilon-RII;
- Gene ID
- 2208
- UniProt ID
- P06734
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Gomiliximab"
Anti-Human CD23 Recombinant Antibody (Gomiliximab)Recombinant monoclonal antibody to CD23. Gomiliximab is a monoclonal antibody acting as an immunosuppressive drug for the treatment of allergic asthma. It targets the low affinity IgE receptor (FcεRII or CD23). The drug is a chimeric antibody from Macaca irus and Homo sapiens.
See other products for "FCER2"
Chimeric Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-231 | Anti-Human CD23 Recombinant Antibody (Gomiliximab) | WB, Neut, ELISA, IF, IP, FuncS, FC | IgG1 - kappa |
Fc Glycosylation
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-157LC | Recombinant Anti-Human FCER2 Antibody (Fc glycosylation/Non fucosylated) | ELISA | Chimeric antibody (primate/human) |
Low- or Non-fucosylated Oligosaccharide
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-157LC-1 | Recombinant Anti-Human FCER2 Antibody (Fc glycosylation/Non fucosylated) | ELISA | Chimeric antibody (primate/human) |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-786CQ | Mouse Anti-FCER2 Recombinant Antibody (clone CBL016) | Neut, FC, WB | Mouse IgG2 |
| NEUT-788CQ | Mouse Anti-FCER2 Recombinant Antibody (clone MM0164-2C23) | WB, Neut, FC | Mouse IgG1 |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-787CQ | Mouse Anti-FCER2 Recombinant Antibody (clone TU1) | FC, IHC-Fr, ICC, WB, Block | Mouse IgG3, κ |
| NEUT-789CQ | Mouse Anti-FCER2 Recombinant Antibody (clone CBL329) | ELISA, WB, Block, CyTOF®, FC | Mouse IgG1 |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1268 | Hi-Affi™ Rabbit Anti-FCER2 Recombinant Antibody (clone DS1268AB) | IHC | Rabbit IgG |
MHC Tetramer for Cancer
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1148-FY-F(E) | Human Anti-FCER2 Recombinant Antibody; Fab Fragment (HPAB-1148-FY-F(E)) | Activ | Human Fab |
| HPAB-1149-FY-F(E) | Monkey Anti-FCER2 Recombinant Antibody; Fab Fragment (HPAB-1149-FY-F(E)) | Activ | Monkey Fab |
| HPAB-0530-YJ-S(P) | Mouse Anti-FCER2 Recombinant Antibody (clone 1E9); scFv Fragment | ELISA, IHC | Mouse scFv |
| HPAB-0531-YJ-S(P) | Human Anti-FCER2 Recombinant Antibody (clone ch1E9); scFv Fragment | ELISA, IHC | Human scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1148-FY-S(P) | Monkey Anti-FCER2 Recombinant Antibody; scFv Fragment (HPAB-1148-FY-S(P)) | Activ | Monkey scFv |
| HPAB-1149-FY-S(P) | Monkey Anti-FCER2 Recombinant Antibody; scFv Fragment (HPAB-1149-FY-S(P)) | Activ | Monkey scFv |
| HPAB-0530-YJ-F(E) | Mouse Anti-FCER2 Recombinant Antibody (clone 1E9); Fab Fragment | ELISA, IHC | Mouse Fab |
| HPAB-0531-YJ-F(E) | Human Anti-FCER2 Recombinant Antibody (clone ch1E9); Fab Fragment | ELISA, IHC | Chimeric (mouse/human) Fab |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-A1301-YJ | Mouse Anti-FCER2 Recombinant Antibody (clone C11) | ELISA | Mouse IgG2a |
| HPAB-A1302-YJ | Human Anti-FCER2 Recombinant Antibody (clone chC11) | ELISA | Chimeric (mouse/human) IgG1 |
| ZG-0096J | Mouse Anti-FCER2 Recombinant Antibody (ZG-0096J) | IHC-P, IF | Mouse IgG |
| ZG-0097J | Mouse Anti-FCER2 Recombinant Antibody (ZG-0097J) | IHC-P, IF | Mouse IgG |
| ZG-0098J | Mouse Anti-FCER2 Recombinant Antibody (clone 10H2) | WB | Mouse IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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