Human Anti-KDR Recombinant Antibody (clone cP1C11) (CAT#: HPAB-A1306-YJ)
This product is a chimeric (mouse/human) antibody that recognizes KDR.
Specific Inquiry
ELISA
Figure 1 Binding of antibodies to KDR.
Zhu, Z., Lu, D., Kotanides, H., Santiago, A., Jimenez, X., Simcox, T., ... & Witte, L. (1999). Inhibition of vascular endothelial growth factor induced mitogenesis of human endothelial cells by a chimeric anti-kinase insert domain-containing receptor antibody. Cancer letters, 136(2), 203-213.
FC
Figure 2 FACS analysis of c-p1C11 binding to KDR-expressing HUVEC.
Zhu, Z., Lu, D., Kotanides, H., Santiago, A., Jimenez, X., Simcox, T., ... & Witte, L. (1999). Inhibition of vascular endothelial growth factor induced mitogenesis of human endothelial cells by a chimeric anti-kinase insert domain-containing receptor antibody. Cancer letters, 136(2), 203-213.
Inhib
Figure 3 Inhibition of binding of KDR to immobilized VEGF165 by antibodies.
Zhu, Z., Lu, D., Kotanides, H., Santiago, A., Jimenez, X., Simcox, T., ... & Witte, L. (1999). Inhibition of vascular endothelial growth factor induced mitogenesis of human endothelial cells by a chimeric anti-kinase insert domain-containing receptor antibody. Cancer letters, 136(2), 203-213.
SPR
Figure 4 Binding kinetics of p1C11 scFv and c-p1C11 to KDR by surface plasmon resonance using the BIAcore system.
Zhu, Z., Lu, D., Kotanides, H., Santiago, A., Jimenez, X., Simcox, T., ... & Witte, L. (1999). Inhibition of vascular endothelial growth factor induced mitogenesis of human endothelial cells by a chimeric anti-kinase insert domain-containing receptor antibody. Cancer letters, 136(2), 203-213.
WB
Figure 5 Inhibition of VEGF-induced phosphorylation of KDR and MAP kinases p44/p42 by anti-KDR antibodies by Western Blot.
Zhu, Z., Lu, D., Kotanides, H., Santiago, A., Jimenez, X., Simcox, T., ... & Witte, L. (1999). Inhibition of vascular endothelial growth factor induced mitogenesis of human endothelial cells by a chimeric anti-kinase insert domain-containing receptor antibody. Cancer letters, 136(2), 203-213.
FuncS
Figure 6 Inhibition of VEGF-induced HUVEC proliferation by anti-KDR antibodies.
Zhu, Z., Lu, D., Kotanides, H., Santiago, A., Jimenez, X., Simcox, T., ... & Witte, L. (1999). Inhibition of vascular endothelial growth factor induced mitogenesis of human endothelial cells by a chimeric anti-kinase insert domain-containing receptor antibody. Cancer letters, 136(2), 203-213.
Block
Figure 7 Serial sections from a 15-day-old oxygen-treated animal immunostained with anti-vWf (A, D), anti-KDR antibody that was preincubated overnight with PBS (B, E), or anti-KDR antibody preincubated overnight with a 10-M excess of soluble KDR (C, F).
Zhu, Z., Lu, D., Kotanides, H., Santiago, A., Jimenez, X., Simcox, T., ... & Witte, L. (1999). Inhibition of vascular endothelial growth factor induced mitogenesis of human endothelial cells by a chimeric anti-kinase insert domain-containing receptor antibody. Cancer letters, 136(2), 203-213.
Specifications
- Host Species
- Human
- Derivation
- Chimeric (mouse/human)
- Type
- Chimeric (mouse/human) IgG1
- Specificity
- Human Plasma cell malignancies
- Species Reactivity
- Human
- Clone
- cP1C11
- Applications
- WB, ELISA, FC, Block, Inhib, FuncS
Product Property
- Purification
- Protein A/G Purified
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the Certificate of Analysis for the lot-specific concentration.
- Buffer
- PBS
- Storage
- Store at 4°C for short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been reported for use in Western Blot, Enzyme-linked Immunosorbent Assay, Flow Cetometry, Blocking, Inhibition, and Functional Assay. Optimal working dilutions must be determined by the end user.
Target
- Alternative Names
- FLK1; CD309; VEGFR; VEGFR2; vascular endothelial growth factor receptor 2; fetal liver kinase-1; kinase insert domain receptor (a type III receptor tyrosine kinase); protein-tyrosine kinase receptor Flk-1; soluble VEGFR2; tyrosine kinase growth factor receptor
- Gene ID
- 3791
- UniProt ID
- P35968
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "KDR"
Intrabody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| IAB-B066(A) | Recombinant Anti-human KDR Intrabody [(D-Arg)9] | FC, IF, FuncS | scFv-(D-Arg)9 |
| IAB-B066(G) | Recombinant Anti-human KDR Intrabody [+36 GFP] | CO-IP, FuncS | scFv-(+36GFP) |
| IAB-B066(T) | Recombinant Anti-human KDR Intrabody [Tat] | IF, ELISA, FuncS | scFv-Tat |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-202 | Humanized Anti-KDR Recombinant Antibody (clone Alacizumab); di - Fab' Fragment | IF, IP, Neut, FuncS, ELISA, FC, ICC | Humanized (from mouse) di - Fab' |
| TAB-411CQ | Anti-Human KDR Recombinant Antibody (HLX06) | ELISA | Humanized antibody |
| TAB-411CQ-S(P) | Anti-Human KDR Recombinant Antibody scFv Fragment (HLX06) | ELISA | Humanized antibody |
| TAB-411CQ-F(E) | Anti-Human KDR Recombinant Antibody Fab Fragment (HLX06) | ELISA | Humanized antibody |
Immunotoxin
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-G047E | Anti-KDR immunotoxin (IgG1)-PE | Cytotoxicity assay, Function study |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-326CQ | Rat Anti-Kdr Recombinant Antibody (TAB-326CQ) | ELISA, IHC | Rat IgG |
| TAB-331CQ | Anti-Human KDR Recombinant Antibody (6.64) | IHC, ELISA | Mouse IgG1 |
| TAB-326CQ-S(P) | Rat Anti-Kdr Recombinant Antibody; scFv Fragment (TAB-326CQ-S(P)) | ELISA, FC, WB | Rat scFv |
| TAB-331CQ-S(P) | Anti-Human KDR Recombinant Antibody scFv Fragment (6.64) | ELISA, FC, IHC | |
| TAB-332CQ-S(P) | Anti-Human KDR Recombinant Antibody scFv Fragment (4.13) | ELISA, FC, IHC |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-322CQ-S(P) | Anti-Human KDR Recombinant Antibody scFv Fragment (AK404R) | ELISA, WB | Human antibody |
| TAB-325CQ-S(P) | Human Anti-KDR Recombinant Antibody; scFv Fragment (TAB-325CQ-S(P)) | ELISA, FC | Human scFv |
| TAB-329CQ-S(P) | Human Anti-KDR Recombinant Antibody; scFv Fragment (TAB-329CQ-S(P)) | ELISA, WB, Neut | Human scFv |
| TAB-330CQ-S(P) | Mouse Anti-KDR Recombinant Antibody; scFv Fragment (TAB-330CQ-S(P)) | ELISA, WB, Neut | Mouse scFv |
| TAB-333CQ-S(P) | Human Anti-KDR Recombinant Antibody; scFv Fragment (TAB-333CQ-S(P)) | ELISA, FC | Human scFv |
Chicken IgY Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0624MZ | Chicken Anti-VEGFR-2 Polyclonal IgY | IHC, WB | Chicken antibody |
| BRD-0709MZ | Chicken Anti-KDR Polyclonal IgY | WB | Chicken antibody |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1619CQ | Recombinant Mouse Anti-KDR Antibody (23B31) | WB, IP, FC, Neut | |
| NEUT-1620CQ | Recombinant Rat Anti-Kdr Antibody (CBL840) | ELISA(Cap), Neut | IgG2a |
| NEUT-1621CQ | Recombinant Rat Anti-Kdr Antibody (CBL880) | Neut, WB | IgG2 |
| NEUT-1622CQ | Recombinant Mouse Anti-KDR Antibody (6B11) | WB, Neut | IgG1 |
| NEUT-1623CQ | Recombinant Mouse Anti-KDR Antibody (CBL505) | FC, CyTOF, Neut | IgG1 |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1927 | Hi-Affi™ Recombinant Rabbit Anti-KDR Monoclonal Antibody (DS1927AB) | IHC-P | IgG |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-1580-CN | Recombinant Rabbit Anti-KDR Monoclonal Antibody (SU03-42) | WB, IF, IHC, IP | Rabbit IgG |
| HPAB-0251-FY | Human Anti-KDR Recombinant Antibody (clone 043HAb-1) | ELISA | Human IgG1 |
| HPAB-0252-FY | Human Anti-KDR Recombinant Antibody (clone 043HAb-2) | ELISA | Human IgG1 |
| HPAB-0253-FY | Human Anti-KDR Recombinant Antibody (clone 043HAb-3) | ELISA | Human IgG1 |
| HPAB-0254-FY | Human Anti-KDR Recombinant Antibody (clone 043HAb-4) | ELISA | Human IgG1 |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-079 | Afuco™ Anti-KDR ADCC Recombinant Antibody (Ramucirumab), ADCC Enhanced | IP, IF, FuncS, FC, Neut, ELISA | ADCC enhanced antibody |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0016-YJ-S(P) | Mouse Anti-KDR Recombinant Antibody; scFv Fragment (HPAB-0016-YJ-S(P)) | RIA, ELISA | Mouse scFv |
| HPAB-0567-WJ-S(P) | Human Anti-KDR Recombinant Antibody; scFv Fragment (HPAB-0567-WJ-S(P)) | ELISA, FC, WB | Human scFv |
| HPAB-0476-FY-S(P) | Mouse Anti-KDR Recombinant Antibody; scFv Fragment (HPAB-0476-FY-S(P)) | Inhib | Mouse scFv |
| HPAB-0502-YJ-S(P) | Human Anti-KDR Recombinant Antibody (clone 1); scFv Fragment | ELISA, FC | Human scFv |
| HPAB-0503-YJ-S(P) | Human Anti-KDR Recombinant Antibody (clone 6); scFv Fragment | ELISA, FC | Human scFv |
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0298-YJ-VHH | Recombinant Human Anti-KDR Nano Antibody (HPAB-0298-YJ-VHH) | Inhib | Human VHH |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0141-WJ-F(E) | Human Anti-KDR Recombinant Antibody (clone 2G1C12); Fab Fragment | ELISA | Human Fab |
| HPAB-1279-FY-S(P) | Mouse Anti-KDR Recombinant Antibody; scFv Fragment (HPAB-1279-FY-S(P)) | ELISA, FC, Inhib | Mouse scFv |
| HPAB-1280-FY-S(P) | Mouse Anti-KDR Recombinant Antibody; scFv Fragment (HPAB-1280-FY-S(P)) | ELISA, FC, Inhib | Mouse scFv |
| HPAB-1281-FY-S(P) | Mouse Anti-KDR Recombinant Antibody; scFv Fragment (HPAB-1281-FY-S(P)) | ELISA, FC, Inhib | Mouse scFv |
| HPAB-1282-FY-S(P) | Mouse Anti-KDR Recombinant Antibody; scFv Fragment (HPAB-1282-FY-S(P)) | ELISA, FC, Inhib | Mouse scFv |
MHC Tetramer for Cancer
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-YF304 | A*24:02/Human VEGFR (SYGVLLWEI) MHC Monomer | MHC Multimer | |
| MHC-YF772 | H-2Db/Human VEGFR2/KDR fragment 1 (FSNSTNDILI) MHC Pentamer | FCM |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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