Human Anti-Lewis Y Recombinant Antibody (clone BR96) (CAT#: FAMAB-1327CQ)
This product is a recombinant human antibody that recognizes Lewis Y. The antibody was purified by affinity chromatography. It can be used in ELISA, IHC.
Specific Inquiry
Cyt
Figure 1 ADCC and CDC assays with anti-Lewisy and Lewisb mAbs.
Anti-Lewisy and Lewisb mAbs, BR96 were screened by chromium release assay for ADCC with human PBMCs on Colo 205.
Noble, P., Spendlove, I., Harding, S., Parsons, T., & Durrant, L. G. (2013). Therapeutic targeting of Lewis y and Lewis b with a novel monoclonal antibody 692/29. PLoS One, 8(2), e54892.
IHC
Figure 2 Binding of BR96 LE to normal tissues.
BR96 was assessed for normal tissue binding by IHC. Normal staining to placenta are represented for BR96.
Noble, P., Spendlove, I., Harding, S., Parsons, T., & Durrant, L. G. (2013). Therapeutic targeting of Lewis y and Lewis b with a novel monoclonal antibody 692/29. PLoS One, 8(2), e54892.
Specifications
- Host Species
- Human
- Type
- Human IgG1
- Specificity
- Le(Y)
- Species Reactivity
- Human
- Clone
- BR96
- Applications
- IHC, Cyt
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been reported for use in Immunohistochemistry and Cytotoxicity.
Target
- Alternative Names
- Lewis Y; LeY
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Lewis Y"
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-1634-VHH | Recombinant Anti-Human Lewis Y VHH Single Domain Antibody | WB, IP, ChiP, Neut, ELISA | Llama VHH |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-730 | Humanized Anti-Lewis Y Recombinant Antibody (clone CBR96) | IP, IF, FuncS, FC, Neut, ELISA, ICC | Humanized (from mouse) IgG1, κ |
| TAB-488CL | Anti-Human Lewis Y Recombinant Antibody (MB 311) | Cyt | Antibody |
| TAB-0015CL | Anti-Lewis Y Recombinant Antibody (MB311) | FC, FuncS | Humanized Antibody |
| TAB-0016CL | Anti-Lewis Y Recombinant Antibody (Hu3s193) | RIA, IHC | Humanized Antibody |
| PABX-003 | Recombinant Human Anti-LewisY Antibody (hu3S193) | WB, IF, FuncS, IHC, Inhib | IgG |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0018CL | Anti-Lewis Y Recombinant Antibody (BR55-2) | Activ, Inhib | |
| TAB-0650CL | Anti-Human Lewis Y Recombinant Antibody (3S193) | Cyt, ELISA | |
| TAB-0018CL-S(P) | Anti-Lewis Y Recombinant Antibody scFv Fragment (BR55-2) | FuncS, Inhib | |
| TAB-0650CL-S(P) | Anti-Human Lewis Y Recombinant Antibody scFv Fragment (3S193) | ELISA | |
| PABX-131-S (P) | Recombinant Mouse Anti-LewisY Antibody scFv Fragment (MBR96) | WB, Neut, FuncS | scFv |
Fc Glycosylation
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-044LC | Recombinant Anti-Human Lewis Y Antibody (Fc glycosylation) | ELISA | Humanized antibody |
| Gly-045LC | Recombinant Anti-Human Lewis Y Antibody (Fc glycosylation) | ELISA | Humanized antibody |
| Gly-103LC | Recombinant Anti-Human Lewis Y Antibody (Fc glycosylation) | ELISA | Humanized antibody |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABX-003-S (P) | Recombinant Human Anti-LewisY Antibody scFv Fragment (hu3S193) | WB, IF, FuncS | scFv |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0207CQ | Mouse Anti-Lewis Y Recombinant Antibody (clone MSL5) | ELISA, FC, IHC | Mouse IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0207CQ-F(E) | Mouse Anti-Lewis Y Recombinant Antibody (clone MSL5); Fab Fragment | FC, IHC | Mouse Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0207CQ-S(P) | Mouse Anti-Lewis Y Recombinant Antibody (clone MSL5); scFv Fragment | FC, IHC | Mouse scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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