Mouse Anti-Ricin Recombinant Antibody (clone 3E1) (CAT#: FAMAB-0310JF)
Recombinant monoclonal antibody specially binds to ricin. 3E1 is a mouse monoclonal antibody that can be useful for antibody-based prophylaxis.
Specific Inquiry
IHC
Figure 1 Effects of ricin on lung tissues.
Tissue from ricin-instilled lung showed perforations in the bronchiolar epithelium, evidence of hemorrhage, and influx of leukocytes.
Wong, J., Korcheva, V., Jacoby, D. B., & Magun, B. (2007). Intrapulmonary delivery of ricin at high dosage triggers a systemic inflammatory response and glomerular damage. The American journal of pathology, 170(5), 1497-1510.
WB
Figure 2 Activation of signaling pathways in lung tissues.
Protein lysates from three mice instilled with saline were harvested 48 hours later and subjected to immunoblotting using antibodies against the phosphorylated forms of ERK, JNK, and p38 MAPK and against the nonphosphorylated form of p38 MAPK (as loading control).
Wong, J., Korcheva, V., Jacoby, D. B., & Magun, B. (2007). Intrapulmonary delivery of ricin at high dosage triggers a systemic inflammatory response and glomerular damage. The American journal of pathology, 170(5), 1497-1510.
ELISA
Figure 3 Binding specificity of the six unique single domain antibody (sdAb) clones on ricin.
The data represent the mean ± S.E.M. of the response of five individual mice.
Anderson, G. P., Matney, R., Liu, J. L., Hayhurst, A., & Goldman, E. R. (2007). Multiplexed fluid array screening of phage displayed anti-ricin single domain antibodies for rapid assessment of specificity. Biotechniques, 43(6), 806-811.
Specifications
- Immunogen
- Ricin
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Ricin
- Species Reactivity
- Ricinus communis
- Clone
- 3E1
- Applications
- WB, ELISA, IHC
- Related Disease
- Ricinism
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The Ricin antibody has been reported in applications of Western Blot, Enzyme-linked Immunosorbent Assay, Immunohistochemistry.
Target
- Alternative Names
- Ricin; Ricinus communis ricin
- Gene ID
- 8261245
- UniProt ID
- P02879
- Function
- Neutralization activity
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABL-318 | Recombinant Mouse Anti-Ricin Antibody (6C2) | Neut, FuncS | IgG |
| PABL-692 | Mouse Anti-Ricin Recombinant Antibody (clone mAb RAC18) | Neut | Mouse IgG |
| HPAB-1607-FY | Human Anti-Ricin Recombinant Antibody (clone REV8) | WB, ELISA, IP | Chimeric (macaque/human) IgG |
| HPAB-1608-FY | Human Anti-Ricin Recombinant Antibody (clone REV7) | WB, ELISA, IP | Chimeric (macaque/human) IgG |
| PABS-0068 | Human Anti-Ricin Recombinant Antibody (PABS-0068) | ELISA, Neut, FuncS | Humanized IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-318 | Recombinant Mouse Anti-Ricin Antibody scFv Fragment (6C2) | Neut, FuncS | scFv |
| FAMAB-0060JF-S(P) | Monkey Anti-Ricin Recombinant Antibody (clone 43RCA); scFv Fragment | WB, ELISA, FuncS | Monkey scFv |
| FAMAB-0310JF-S(P) | Mouse Anti-Ricin Recombinant Antibody (clone 3E1); scFv Fragment | WB, ELISA, FuncS | Mouse scFv |
| PSBS-0050 | Mouse Anti-Ricin Recombinant Antibody; scFv Fragment (PSBS-0050) | ELISA, Neut, FuncS | Mouse scFv |
| PSBS-0068 | Human Anti-Ricin Recombinant Antibody; scFv Fragment (PSBS-0068) | ELISA, Neut, FuncS | Humanized scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-318 | Recombinant Mouse Anti-Ricin Antibody Fab Fragment (6C2) | Neut, FuncS | Fab |
| PFBL-685 | Mouse Anti-Ricin Recombinant Antibody (clone mAb RAC18); Fab Fragment | Neut | Mouse Fab |
| PSBZ-192 | Mouse Anti-Ricin Recombinant Antibody (clone RAC18); scFv Fragment | Neut | Mouse scFv |
| PFBS-0050 | Mouse Anti-Ricin Recombinant Antibody; Fab Fragment (PFBS-0050) | ELISA, Neut, FuncS | Mouse Fab |
| PFBS-0068 | Human Anti-Ricin Recombinant Antibody; Fab Fragment (PFBS-0068) | ELISA, Neut, FuncS | Humanized Fab |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABX-165 | Recombinant Mouse Anti-Ricin Antibody (RAC18) | FuncS, IF | IgG |
| PABX-165-S (P) | Recombinant Mouse Anti-Ricin Antibody scFv Fragment (RAC18) | Neut, FuncS | scFv |
| PABX-165-F (E) | Recombinant Mouse Anti-Ricin Antibody Fab Fragment (RAC18) | Neut, FuncS | Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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