CD19 & CD22
Lymphocytes proliferate and differentiate in response to various concentrations of different antigens. The ability of the B cell to respond in a specific, yet sensitive manner to the various antigens is achieved with the use of low-affinity antigen receptors. This gene encodes a cell surface molecule which assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation.
Predicted to enable CD4 receptor binding activity; protein phosphatase binding activity; and sialic acid binding activity. Involved in B cell activation; negative regulation of B cell receptor signaling pathway; and regulation of endocytosis. Located in early endosome and recycling endosome.
Derivation: Mouse
Species Reactivity: Human
Type: Mouse IgG1
Application: WB, FC, ICC, IF, FuncS
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Species Reactivity: Human
Type: Mouse IgG1, κ
Application: IF, FC
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Derivation: Mouse
Species Reactivity: Human
Type: Fab
Application: IP, RIA, FuncS
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Derivation: Mouse
Species Reactivity: Human
Type: scFv
Application: ELISA, WB, IF, FuncS
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Species Reactivity: Human
Application: Cytotoxicity assay, Function study
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Derivation: Human
Species Reactivity: Human
Type: Antibody
Application: FC, ADCC, FuncS
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Species Reactivity: Human
Application: Cytotoxicity assay, Functional assay
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Species Reactivity: Human
Application: Cytotoxicity assay, Function study
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Derivation: Humanized (from mouse)
Species Reactivity: Human
Type: Humanized (from mouse) IgG4, κ
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
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Species Reactivity: Human
Application: Cytotoxicity assay, Function study
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Species Reactivity: Human
Application: Cytotoxicity assay, Function study
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Derivation: Mouse
Species Reactivity: Human
Type: Fv - disulfide stabilized
Application: FuncS, IF, Neut, ELISA, FC, IP, ICC
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Species Reactivity: Human
Application: Cytotoxicity assay, Function study
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Species Reactivity: Human
Application: Cytotoxicity assay, Function study
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Species Reactivity: Human
Application: Cytotoxicity assay, Function study
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Derivation: Humanized
Species Reactivity: Human
Type: Humanized IgG1, κ
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
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Derivation: Humanized
Species Reactivity: Human
Type: IgG1 - kappa
Application: IF, IP, Neut, FuncS, ELISA, FC, WB
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Derivation: Humanized (from mouse)
Species Reactivity: Human
Type: Humanized (from mouse) IgG1, κ
Application: FC, IP, ELISA, Neut, FuncS, IF, ICC
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Derivation: Humanized (from mouse)
Species Reactivity: Human
Type: IgG1
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
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Derivation: Mouse
Species Reactivity: Human
Type: Mouse IgG1, κ
Application: ELISA, IP, FC, FuncS, Neut, IF, ICC
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