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Anti-NTRK2 Therapeutic Antibody scFv Fragment (29D7) (TAB-176CQ-S(P))

The monoclonal antibody recognizes loop-3 of the IgG-1 segment of human TrkB (ENLVGED) and may also recognizes loop-1 of the IgG-1 segment of human TrkB (AGDPVP) and blocks caspase-3 activation caused by hypoxic-ischemic (HI) injury.      

Specifications
Immunogen
TrkB-ECD
Host
Mouse
Specificity
Human
Species Reactivity
Human, Mouse
Clone
29D7
Applications
Used for immunoassay techniques such as: Enzyme-linked Immunosorbent Assay; Flow Cytometry; Western Blot
Related Disease
Alzheimer's disease, Parkinson's disease, Huntington's chorea, amyotrophic lateral sclerosis (ALS)
Target
Alternative Names
NTRK2; Neurotrophic receptor tyrosine kinase 2; TRKB; trk-B; GP145-TrkB; BDNF/NT-3 growth factors receptor; tyrosine kinase receptor B; tropomyosin-related kinase B
Entrez Gene ID
4915
UniProt ID
Q16620

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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