Provided are TrkB agonist antibodies, which can be used in the treatment of peripheral neuropathies, such as Charcot-Marie-Tooth disease. The antibody can be used for immunoassay techniques such as: Function Assay as a agonist.
Figure 1 The relative amount of neuron survival in the presence of increasing amounts of several agonist anti-TrkB humanized antibodies using an in vitro assay.
Top graph: agonist anti-TrkB humanized antibodies C1, C2, 4A6 and 4B12. Bottom graph: various isotype forms of agonist anti-TrkB humanized antibody RN1026A (1026A). Mouse monoclonal agonist anti-TrkB antibody 38B8 and/or BDNF are used positive controls. The y-axis indicates the number of neurons, and x-axis indicates the concentration of antibody (or BDNF) in pM.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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CAT | Product Name | Application | Type |
---|---|---|---|
TAB-177CQ | Anti-Human NTRK2 Recombinant Antibody (C2) | Agonist, FuncS | Humanized antibody |
TAB-178CQ | Anti-Human NTRK2 Recombinant Antibody (A2) | ELISA, FC | Humanized antibody |
TAB-179CQ | Anti-Human NTRK2 Recombinant Antibody (RN1026A) | ELISA, FC | Humanized antibody |
TAB-177CQ-S(P) | Anti-Human NTRK2 Recombinant Antibody scFv Fragment (C2) | ELISA, FC | Humanized antibody |
TAB-178CQ-S(P) | Anti-Human NTRK2 Recombinant Antibody scFv Fragment (A2) | ELISA, FC | Humanized antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-180CQ | Anti-Human NTRK2 Recombinant Antibody (C20) | FuncS | Human antibody |
TAB-180CQ-S(P) | Anti-Human NTRK2 Recombinant Antibody scFv Fragment (C20) | ELISA, FC, WB | Human antibody |
TAB-180CQ-F(E) | Anti-Human NTRK2 Recombinant Antibody Fab Fragment (C20) | ELISA, FC, WB | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-171CQ-F(E) | Anti-Human NTRK2 Recombinant Antibody Fab Fragment (18H6) | ELISA, FC | |
TAB-172CQ-F(E) | Anti-Human NTRK2 Recombinant Antibody Fab Fragment (38B8) | ELISA, FC | |
TAB-173CQ-F(E) | Anti-Human NTRK2 Recombinant Antibody Fab Fragment (6B72C5) | ELISA, WB, IP | |
TAB-174CQ-F(E) | Anti-Human NTRK2 Recombinant Antibody Fab Fragment (5G5D2B5) | ELISA, WB, IP | |
TAB-175CQ-F(E) | Anti-Human NTRK2 Recombinant Antibody Fab Fragment (17D11) | ELISA, FC, WB |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-2509 | Hi-Affi™ Recombinant Rabbit Anti-NTRK2 Monoclonal Antibody (DS2509AB) | WB, IHC, IP | IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
NS-095CN | Human Anti-NTRK2 Recombinant Antibody (NS-095CN) | ELISA | Human IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
NS-095CN-S(P) | Human Anti-NTRK2 Recombinant Antibody; scFv Fragment (NS-095CN-S(P)) | ELISA | Human scFv |
HPAB-0662-CN-S(P) | Human Anti-NTRK2 Recombinant Antibody; scFv Fragment (HPAB-0662-CN-S(P)) | ELISA, Neut | Human scFv |
HPAB-0663-CN-S(P) | Human Anti-NTRK2 Recombinant Antibody; scFv Fragment (HPAB-0663-CN-S(P)) | ELISA, Neut | Human scFv |
HPAB-0664-CN-S(P) | Human Anti-NTRK2 Recombinant Antibody; scFv Fragment (HPAB-0664-CN-S(P)) | ELISA, Neut | Human scFv |
HPAB-0665-CN-S(P) | Human Anti-NTRK2 Recombinant Antibody; scFv Fragment (HPAB-0665-CN-S(P)) | ELISA, Neut | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
PFBC-458 | Mouse Anti-NTRK2 Recombinant Antibody (clone AB20); Fab Fragment | ELISA, FC, IF, Agonist | Mouse Fab |
HPAB-AP761-YC-F(E) | Human Anti-NTRK2 Recombinant Antibody (clone 4A6); Fab Fragment | Agonist, FuncS | Humanized Fab |
HPAB-AP762-YC-F(E) | Human Anti-NTRK2 Recombinant Antibody (clone 4B12); Fab Fragment | Agonist, FuncS | Humanized Fab |
HPAB-AP763-YC-F(E) | Human Anti-NTRK2 Recombinant Antibody (clone C1); Fab Fragment | Agonist, FuncS | Humanized Fab |
HPAB-AP764-YC-F(E) | Human Anti-NTRK2 Recombinant Antibody (clone 4B12-17); Fab Fragment | Agonist | Humanized Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-AP761-YC | Human Anti-NTRK2 Recombinant Antibody (clone 4A6) | FuncS | Humanized IgG |
HPAB-AP762-YC | Human Anti-NTRK2 Recombinant Antibody (clone 4B12) | FuncS | Humanized IgG |
HPAB-AP764-YC | Human Anti-NTRK2 Recombinant Antibody (clone 4B12-17) | Agonist | Humanized IgG |
HPAB-AP765-YC | Human Anti-NTRK2 Recombinant Antibody (clone 4B12-15) | Agonist | Humanized IgG |
HPAB-AP766-YC | Human Anti-NTRK2 Recombinant Antibody (clone 4B12-27) | Agonist | Humanized IgG |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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