Mouse Anti-F3 Recombinant Antibody (clone 10H10) (CAT#: PABC-450)

This product is a recombinant Mouse antibody that can recognize F3. Murine antibody 10H10 raised against human tissue factor is unique in that it blocks the signaling pathway, and thus inhibits angiogenesis and tumor growth without interfering with coagulation.


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  • Purity:
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  • Published Data
  • Gene Expression
  • Datasheet
  • MSDS
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Inhib

Figure 1 Cell spreading of HaCaT keratinocytes on anti-TF involves several β1 integrins.

Figure 1 Cell spreading of HaCaT keratinocytes on anti-TF involves several β1 integrins.

Morphology of HaCaT human keratinocytes plated for 3 h on the indicted anti-TF antibodies (50 μg/ml coating concentration) or BSA.

Dorfleutner, A., Hintermann, E., Tarui, T., Takada, Y., & Ruf, W. (2004). Cross-talk of integrin α3β1 and tissue factor in cell migration. Molecular biology of the cell, 15(10), 4416-4425.


Specifications

  • Immunogen
  • The human TF ECD
  • Host Species
  • Mouse
  • Type
  • Mouse IgG1, κ
  • Specificity
  • Human F3
  • Species Reactivity
  • Human
  • Clone
  • 10H10
  • Applications
  • ELISA, FuncS

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • This antibody has been reported for use in Inhibition.

Target

  • Alternative Names
  • F3; coagulation factor III (thromboplastin, tissue factor); TF; TFA; CD142; tissue factor;

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone 10H10"

See other products for "F3"

Deglycosylated Antibody (Non-glycosylated IgGs)

CAT Product Name Application Type
Gly-178LC Recombinant Anti-Human F3 Antibody (Non-glycosylated) ELISA Human antibody

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-1226 Hi-Affi™ Rabbit Anti-F3 Recombinant Antibody (clone DS1226AB) WB, IHC-P, ICC, IF Rabbit IgG

Human Antibody

CAT Product Name Application Type
TAB-473CQ Anti-Human F3 Recombinant Antibody (Tisotumab) ELISA, IHC, FC, IP, IF, Inhib IgG1, κ

Epitope-Specific Antibody

CAT Product Name Application Type
EPAF-0573CQ Mouse Anti-F3 Recombinant Antibody (clone hATR-5) ELISA, Inhib Mouse IgG4

Recombinant Antibody

CAT Product Name Application Type
HPAB-0172CQ Human Anti-F3 Recombinant Antibody (HPAB-0172CQ) ELISA, FC, ADCC Chimeric (mouse/human) IgG1
HPAB-0173CQ Human Anti-F3 Recombinant Antibody (HPAB-0173CQ) ELISA, FC, ADCC Chimeric (mouse/human) IgG1, λ
HPAB-0174CQ Human Anti-F3 Recombinant Antibody (HPAB-0174CQ) ELISA, FC, ADCC Chimeric (mouse/human) IgG1, λ
HPAB-0175CQ Human Anti-F3 Recombinant Antibody (HPAB-0175CQ) ELISA, WB, Inhib Humanized IgG1, κ
HPAB-J0088-YC Human Anti-F3 Recombinant Antibody (HPAB-J0088-YC) ELISA, FC, IHC, FuncS Human IgG1

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-473CQ Afuco™ Anti-F3 ADCC Recombinant Antibody (Tisotumab), ADCC Enhanced ELISA, IHC, FC, IP, IF, Inhib ADCC enhanced antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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