Mouse Anti-MST1R Recombinant Antibody (clone 07F01) (CAT#: HPAB-687-FY)

This product is a recombinant antibody that recognizes MST1R. The monoclonal antibody 07F01 reacts with the epitope of MST1R. antibody 07F01 inhibits MSP induced ERK phosphorylation in T47D cells. This antibody can be used to treat certain forms of cancer that are associated with activation of RON.


Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Fc Engineering:
  • Published Data
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Neut

Figure 1 Anti-RON antibodies potently inhibit MSP binding to RON.

Figure 1 Anti-RON antibodies potently inhibit MSP binding to RON.

Neutralization of ligand binding.

Inhib

Figure 2 Anti-RON antibodies potently inhibit MSP binding to RON.

Figure 2 Anti-RON antibodies potently inhibit MSP binding to RON.

Anti-RON antibodies inhibit MSP-induced signaling in T47D Cells.

Inhib

Figure 3 Anti-RON mAbs inhibit RON receptor-driven tumorigenesis.

Figure 3 Anti-RON mAbs inhibit RON receptor-driven tumorigenesis.

Proprietary Directed Complemented (DC) breast tumor model driven by WT RON.

Cyt

Figure 4 07F01 decreases proliferation (Ki67) and increases apoptosis (TUNEL) in WT RON DC tumors.

Figure 4 07F01 decreases proliferation (Ki67) and increases apoptosis (TUNEL) in WT RON DC tumors.

ELISA

Figure 5 Pharmacokinetic parameters of 29B06 and 07F01.

Figure 5 Pharmacokinetic parameters of 29B06 and 07F01.


Specifications

  • Host Species
  • Mouse
  • Type
  • Mouse IgG
  • Specificity
  • Human MST1R
  • Species Reactivity
  • Human
  • Clone
  • 07F01
  • Applications
  • Neut, Inhib, Cyt, ELISA

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • The MST1R antibody has been reported in applications of Neutralization, Inhibition, Cytotoxicity, Enzyme-linked Immunosorbent Assay.

Target

  • Alternative Names
  • RON; PTK8; CD136; NPCA3; CDw136

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone 07F01"

See other products for "MST1R"

Blocking Antibody

CAT Product Name Application Type
NEUT-1756CQ Recombinant Mouse Anti-MST1R Antibody (CBL312) BL IgG1

Neutralizing Antibody

CAT Product Name Application Type
NEUT-1757CQ Recombinant Mouse Anti-MST1R Antibody (MM0478-10F24) Neut IgG1

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-2309 Hi-Affi™ Recombinant Rabbit Anti-MST1R Monoclonal Antibody (DS2309AB) FC, ICC/IF, IHC-P, IP, WB IgG

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-184 Afuco™ Anti-MST1R ADCC Recombinant Antibody (Narnatumab), ADCC Enhanced FuncS, IF, Neut, ELISA, FC, IP ADCC enhanced antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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