Popular Searches: Recombinant Antibody MHC Tetramer T cell Receptor Scaffold Protein
  • Home
  • MST1R
  • Human Anti-MST1R Recombinant Antibody (clone Ch07F01 C102S)

Human Anti-MST1R Recombinant Antibody (clone Ch07F01 C102S) (CAT#: HPAB-J0190-YC)

Monoclonal antibodies that bind and inhibit activation of human RON (Recepteur d'Origine Nantais) are disclosed. The antibodies can be used to treat certain forms of cancer that are associated with activation of RON. It has shown that antibodies 07F01, 12B11, 17F06, 18H09 and 29B06 each inhibited MSP induced ERK phosphorylation in T47D cells, while only antibodies 07F01, 18H09 and 29B06 each blocked MSP binding to hRON SEMA+PSI in the neutralization assay. This suggests that antibodies 12B11 and 17F06 do not neutralize binding of MSP to the hRON SEMA+PSI domain, neutralize binding of MSP to RON in the context of the full RON extracellular domain, or function by a mechanism other than blocking MSP binding to RON.


See more Engineered Antibody products for MST1R
Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Fc Engineering:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8180/44_E6_1_selected.jpg
Normal Tissue
Figure 2 Cerebral cortex
Figure 2 Cerebral cortex
(Glial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8180/22751_B_8_5.jpg
Figure 3 Colon
Figure 3 Colon
(Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8180/22751_A_7_3.jpg
Figure 4 Liver
Figure 4 Liver
(Cholangiocytes Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Hepatocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8180/22751_A_7_4.jpg
Figure 5 Kidney
Figure 5 Kidney
(Cells in glomeruli Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8180/22751_A_9_5.jpg
Figure 6 Testis
Figure 6 Testis
(Cells in seminiferous ducts Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Leydig cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8180/22751_A_6_6.jpg
Figure 7 Skin
Figure 7 Skin
(Fibroblasts Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Keratinocytes Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Melanocytes Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8180/22751_B_8_1.jpg
Figure 8 Lymph node
Figure 8 Lymph node
(Germinal center cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/8180/22751_A_8_8.jpg
RNA Expression
Figure 9 RNA cell line category: Cell line enhanced (A-431, CAPAN-2, HaCaT, HBEC3-KT, hTCEpi, RT4)
Figure 9 RNA cell line category: Cell line enhanced (A-431, CAPAN-2, HaCaT, HBEC3-KT, hTCEpi, RT4)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000164078-MST1R

Specifications

  • Immunogen
  • Recombinant human RON extracellular domain (hRON-ECD)
  • Host Species
  • Human
  • Derivation
  • Chimeric (mouse/human)
  • Type
  • Chimeric (mouse/human) IgG1, κ
  • Specificity
  • Human MST1R
  • Species Reactivity
  • Human
  • Clone
  • Ch07F01 C102S
  • Applications
  • ELISA, Neut, FuncS

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • Macrophage Stimulating 1 Receptor; PTK8 Protein Tyrosine Kinase 8; C-Met-Related Tyrosine Kinase; MSP Receptor; EC 2.7.10.1; P185-Ron; CDw136; PTK8

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone Ch07F01 C102S"

See other products for "MST1R"

Human Antibody

CAT Product Name Application Type
TAB-184 Anti-Human RON Recombinant Antibody (Narnatumab) FuncS, IF, Neut, ELISA, FC, IP, ICC IgG1 - kappa
TAB-332CT-S(P) Anti-Human RON Recombinant Antibody scFv Fragment (e01h6) WB, ELISA, FC Human antibody
TAB-333CT-S(P) Human Anti-MST1R Recombinant Antibody; scFv Fragment (TAB-333CT-S(P)) WB, ELISA, FC, IP Human scFv
TAB-332CT-F(E) Anti-Human RON Recombinant Antibody Fab Fragment (e01h6) WB, ELISA, FC Human antibody
TAB-333CT-F(E) Human Anti-MST1R Recombinant Antibody; Fab Fragment (TAB-333CT-F(E)) WB, ELISA, FC, IP Human Fab

Mouse Antibody

CAT Product Name Application Type
TAB-331CT-S(P) Anti-Human RON Recombinant Antibody scFv Fragment (11H09) WB, ELISA, FC
TAB-334CT-S(P) Mouse Anti-MST1R Recombinant Antibody; scFv Fragment (TAB-334CT-S(P)) WB, ELISA, FC, IP Mouse scFv
TAB-335CT-S(P) Mouse Anti-MST1R Recombinant Antibody; scFv Fragment (TAB-335CT-S(P)) WB, ELISA, FC, IP Mouse scFv
TAB-331CT-F(E) Anti-Human RON Recombinant Antibody Fab Fragment (11H09) WB, ELISA, FC
TAB-334CT-F(E) Mouse Anti-MST1R Recombinant Antibody; Fab Fragment (TAB-334CT-F(E)) WB, ELISA, FC, IP Mouse Fab

Blocking Antibody

CAT Product Name Application Type
NEUT-1756CQ Recombinant Mouse Anti-MST1R Antibody (CBL312) BL IgG1

Neutralizing Antibody

CAT Product Name Application Type
NEUT-1757CQ Recombinant Mouse Anti-MST1R Antibody (MM0478-10F24) Neut IgG1

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-2309 Hi-Affi™ Recombinant Rabbit Anti-MST1R Monoclonal Antibody (DS2309AB) FC, ICC/IF, IHC-P, IP, WB IgG

scFv Fragment Antibody

CAT Product Name Application Type
HPAB-0135-FY-S(P) Human Anti-MST1R Recombinant Antibody (clone sh29B06-78); scFv Fragment WB Humanized scFv
HPAB-0821-CN-S(P) Human Anti-MST1R Recombinant Antibody (clone MOR07692); scFv Fragment WB, ELISA, FC Human scFv
HPAB-0823-CN-S(P) Human Anti-MST1R Recombinant Antibody (clone MOR07919); scFv Fragment WB, ELISA, FC Human scFv
HPAB-0706-FY-F(E) Mouse Anti-MST1R Recombinant Antibody (clone AB005); scFv Fragment ELISA Mouse scFv
HPAB-0720-FY-F(E) Mouse Anti-MST1R Recombinant Antibody (clone AB034); scFv Fragment ELISA Mouse scFv

Recombinant Antibody

CAT Product Name Application Type
HPAB-0821-CN Human Anti-MST1R Recombinant Antibody (clone MOR07692) WB, ELISA, FC Human IgG1, κ
HPAB-0823-CN Human Anti-MST1R Recombinant Antibody (clone MOR07919) WB, ELISA, FC Human IgG1, κ
MRO-1343-CN Recombinant Rabbit Anti-MST1R Monoclonal Antibody (CBACN-488) WB, IF, IHC, IP, FC Rabbit IgG
MRO-2169-CN Rabbit Anti-MST1R Polyclonal Antibody (MRO-2169-CN) IF, IHC Rabbit IgG
HPAB-1407-FY Mouse Anti-MST1R Recombinant Antibody (clone RON6) ELISA, Inhib, WB Mouse IgG

Fab Fragment Antibody

CAT Product Name Application Type
HPAB-0821-CN-F(E) Human Anti-MST1R Recombinant Antibody (clone MOR07692); Fab Fragment WB, ELISA, FC Human Fab
HPAB-0823-CN-F(E) Human Anti-MST1R Recombinant Antibody (clone MOR07919); Fab Fragment WB, ELISA, FC Human Fab
HPAB-1407-FY-S(P) Mouse Anti-MST1R Recombinant Antibody (clone RON6); Fab Fragment ELISA, Inhib Mouse Fab
HPAB-1408-FY-S(P) Mouse Anti-MST1R Recombinant Antibody (clone RON8); Fab Fragment ELISA, Inhib Mouse Fab
HPAB-J0189-YC-F(E) Mouse Anti-MST1R Recombinant Antibody (clone 17F06); Fab Fragment ELISA, Neut, FuncS Mouse Fab

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-184 Afuco™ Anti-MST1R ADCC Recombinant Antibody (Narnatumab), ADCC Enhanced FuncS, IF, Neut, ELISA, FC, IP ADCC enhanced antibody

Customer Reviews and Q&As

Submit a review or a question
There are currently no Customer reviews or questions for HPAB-J0190-YC. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.

For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Send Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

© 2024 Creative Biolabs.
  • 0
  • 0
Cart
    Inquiry

    Go to compare