Anti-Human IL10 Recombinant Antibody (SCH708980) (CAT#: TAB-390CL)
Recombinant Humanized monoclonal antibody expressed in CHO binding to Human IL10. This is a humanized anti-IL-10 antibody under investigation as an anti-immunosuppressive agent during visceral Leishmaniasis. Of note, there are no ongoing clinical trials that evaluate the therapeutic potential of cytokines from the IL-10 family (or their inhibitors) in cancer patients.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 Cerebral cortex
(Neuronal cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/71391/167603_B_9_5.jpg
(Neuronal cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/71391/167603_B_9_5.jpg
Figure 2 Testis
(Leydig cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/71391/167603_A_6_6.jpg
(Leydig cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/71391/167603_A_6_6.jpg
Figure 3 RNA cell line category: Group enriched (HMC-1, U-266/70)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000136634-IL10
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000136634-IL10
Figure 3 RNA cell line category: Group enriched (HMC-1, U-266/70)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000136634-IL10
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000136634-IL10
Specifications
- Derivation
- Humanized
- Type
- Antibody
- Species Reactivity
- Human
- Related Disease
- Autoimmune Diseases
Product Property
- Purity
- >95% as judged by SDS-polyacrylamide gel electrophoresis
- Storage
- 4°C. For long term storage, aliquot and store at -20°C. Repeated thawing and freezing must be avoided.
Target
- Alternative Names
- IL10; interleukin 10; CSIF; TGIF; GVHDS; IL-10; IL10A; interleukin-10; T-cell growth inhibitory factor; cytokine synthesis inhibitory factor
- Gene ID
- 3586
- UniProt ID
- P22301
Related Resources
Asthma
Inflammatory Bowel Diseases
Systemic Lupus Erythematosus
Autoimmune Thyroid Disease
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBW-080 | Rat Anti-IL10 Recombinant Antibody (clone 9D7); Fab Fragment | Neut | Rat Fab |
| HPAB-0022-YC-F(E) | Human Anti-IL10 Recombinant Antibody; Fab Fragment (HPAB-0022-YC-F(E)) | ELISA, Neut | Humanized Fab |
| HPAB-0223CQ-F(E) | Mouse Anti-IL10 Recombinant Antibody (clone B-N10); Fab Fragment | ELISA, FC, Block | Mouse Fab |
| HPAB-0224CQ-F(E) | Human Anti-IL10 Recombinant Antibody (clone BT-063); Fab Fragment | ELISA, FC, Block | Humanized Fab |
| HPAB-0344-WJ-F(E) | Human Anti-IL10 Recombinant Antibody (clone 12G8); Fab Fragment | ELISA | Humanized Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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