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Formats

Introduction Products Advantages

Creative Biolabs is a company specializing in the research and production of antibodies, backed by years of industry experience and a highly skilled professional team. As your reliable antibody supplier, we adhere to the principle of "quality first, customer foremost," and can supply the finest array of antibody products in various formats.

Introduction

In the fast-changing world of biotechnology, antibodies have become essential bioreagents with significant promise. Creative Biolabs is excited to introduce our unique collection of six antibody format products, tailored to fulfill diverse requirements from fundamental detection to specialized analysis assays. Our products showcase outstanding performance and quality, utilizing state-of-the-art technology and creative approaches to foster groundbreaking progress in both scientific research and therapeutic applications.

Schematic Representation of Different Antibody Formats.Fig.1 Different Antibody Formats.1,8

Products

In the field of antibody development, we remain at the forefront, dedicated to delivering a diverse range of high-performance solutions to meet your research and preclinical needs. At Creative Biolabs, our six distinct types of antibody products are each unique and powerful, empowering you to usher in a new era of drug discovery.

mRNA Encoded Antibody


Diagram of the Basic Structure of Self-amplifying mRNA (RepRNA) for the Production of mRNA Encoded Antibody.

Our mRNA-encoded antibody products merge genetic engineering with synthetic biology, heralding a new era in antibody production. These intelligent antibodies leverage intracellular translation mechanisms to swiftly and flexibly adapt to changing medical requirements. Whether for vaccine development or targeted therapies, they offer remarkable expression efficiency and stability, giving you a competitive edge in tackling emerging diseases.

IgG Antibody


As the most prevalent type of antibody, our IgG antibody products are renowned for their exceptional specificity and affinity. Rigorously selected and optimized, these IgG antibodies maintain high performance across a variety of experimental conditions, making them suitable for diagnostics, therapeutics, and research applications. Additionally, our IgG antibodies feature an optimized Fc structure, enhancing their efficacy and half-life, thus providing more effective treatment options.

IgG Antibody Synthesis with the Standard PURE System.

Fab Antibody


Schematic Representation of IgG, F(ab’)2, Fab, and scFv Fragments.

Our Fab antibody products are the ideal choice for small-molecule drugs and targeted therapies. They are particularly suited for oncology treatments and precision medicine, offering flexibility and efficiency in your research endeavors.

ScFv Antibody


ScFv antibodies are a standout feature of our antibody product line. Their compact and adaptable nature enables them to rapidly penetrate cell membranes and target intracellular sites for therapy. Our ScFv antibody products are especially valuable in studying intracellular targets, empowering scientists to expand the boundaries of antibody applications and drive discoveries.

Structure of Conventional Antibody and Single-chain Variable Fragment (scFv).

Hexamer Antibody


Overview of the IgG1 Antibody Hexamer Observed in the IgG1-b12 Crystal Structure.

Hexamer antibody products introduce an innovative structure that leverages their synergistic effects to deliver unparalleled detection capabilities in complex biological samples. This stable structure formed through polymerization maximizes efficacy, enhancing antigen recognition and signal amplification, thus representing a breakthrough for next-generation precision diagnostics and targeted therapies.

IgM Antibody


Our distinctive IgM antibody products feature polyvalent binding and high affinity. As the first responders of the immune system, IgM plays a crucial role in the elimination of pathogens. Our IgM products are meticulously designed to offer enhanced immune recognition capabilities, significantly increasing the sensitivity and specificity of immune assays, and thereby facilitating early disease diagnosis.

The cryo-EM Structure of FL-IgM.

Advantages

Whether in fundamental research or new drug development, Creative Biolabs is committed to offering clients the most valuable solutions, supporting scientific advancements and a healthier future. Our selection of antibody products showcases exceptional effectiveness and adaptability for a wide array of applications, while also establishing industry benchmarks through their unique and innovative designs.

  • Diverse Antibody Products: Creative Biolabs offers a wide range of antibody types to cater to various research needs.
  • High-Quality Products: Our top-notch antibody products undergo rigorous testing and validation, ensuring reliable experimental outcomes.
  • Expert Technical Support: We provide professional technical assistance to help customers select the right antibodies and address any challenges encountered during experiments.
  • Custom Services: Creative Biolabs also offers custom antibody services, allowing clients to design antibodies according to specific requirements, such as target antigens and host animals.
  • Timely Supply: We maintain a steady inventory and provide prompt shipping services to ensure our customers receive their antibody products quickly.
  • Versatile Experimental Applications: Our antibody products are suitable for a wide array of experimental techniques, including ELISA, Western blot, immunohistochemistry, and flow cytometry.
  • Excellent After-Sales Service: We continuously improve our products based on customer feedback and offer after-sales support to ensure customer satisfaction.

As a leading supplier of antibodies in the industry, Creative Biolabs can deliver high-quality products and expert services to our customers. Our extensive range of antibodies encompasses a variety of targets, including but not limited to cellular signaling pathways, immunology, and cell biology, ensuring that we can meet diverse research needs. If you would like to learn more about our antibody products, please feel free to contact us at any time.

References
  1. Alfaleh, Mohamed A., et al. "Phage display derived monoclonal antibodies: from bench to bedside." Frontiers in immunology 11 (2020): 1986.
  2. Deal, Cailin E., Andrea Carfi, and Obadiah J. Plante. "Advancements in mRNA encoded antibodies for passive immunotherapy." Vaccines 9.2 (2021): 108.
  3. Murakami, Satoshi, Rena Matsumoto, and Takashi Kanamori. "Constructive approach for synthesis of a functional IgG using a reconstituted cell-free protein synthesis system." Scientific Reports 9.1 (2019): 671.
  4. Jagdale, Prabhas, Ashwni Verma, and Dhaval K. Shah. "Pulmonary Pharmacokinetics of Antibody and Antibody Fragments Following Systemic and Local Administration in Mice." Pharmaceutics 16.10 (2024): 1259.
  5. Haddad, Fatma, et al. "A Comprehensive Review on Therapeutic Potential of Nanobodies." (2023).
  6. de Jong, Rob N., et al. "A novel platform for the potentiation of therapeutic antibodies based on antigen-dependent formation of IgG hexamers at the cell surface." PLoS Biology 14.1 (2016): e1002344.
  7. Chen, Qu, et al. "Cryomicroscopy reveals the structural basis for a flexible hinge motion in the immunoglobulin M pentamer." Nature Communications 13.1 (2022): 6314.
  8. Distributed under Open Access license CC BY 4.0, without modification.

For Research Use Only. Not For Clinical Use.

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