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AbPlus

Introduction Products Features

As one of the leading antibody manufacturers in the world, Creative Biolabs brings nearly 100,000 antibody varieties to perfectly meet your needs. Our AbPlus antibody platform is supported by a skilled and specialized R&D team that has garnered support from clients worldwide. Our AbPlus product redefines what it means to achieve peak performance. Designed with precision and crafted from the highest quality materials, AbPlus offers unparalleled efficiency and functionality.

Introduction

In recent years, there has been a growing emergence of non-traditional forms of antibodies, including bispecific antibodies, antibody fragments, and antibody-drug conjugates (ADCs). Creative Biolabs predicts that non-traditional antibodies will gradually dominate the market. Beyond their use as standalone therapeutics, antibodies will play a crucial role in various other treatment modalities. The integration of antibody therapeutics with other treatment approaches is expected to strengthen significantly over the next 5 to 10 years. These integrations may facilitate the targeted delivery of small molecules, nucleic acids, cytokines, enzymes, and more, or equip engineered therapeutic cells with precise targeting navigation systems, or enhance the safety, efficacy, pharmacokinetics, pharmacodynamics, and drug-likeness of other forms of medication. In response to this trend, we are launching a variety of AbPlus products that encompass various combination therapies involving antibodies, such as antibody + cytokine and antibody + toxin.

Schematic Representation of the Diversity of Immunocytokine Formats. Fig.1 The Diversity of Immunocytokine Assays.1,3

Products

Antibody Magnetic Beads

At Creative Biolabs, the AbPlus antibody magnetic beads product line utilizes our unique nano-surface technology to orientedly coat antibodies onto the surface of magnetic microspheres. Our product offers enhanced antibody binding capacity and reduced nonspecific protein adsorption rates. The elution conditions are more consistent, enabling the one-step purification of antibodies from serum samples with a purity exceeding 90%. These magnetic microspheres are at the nanoscale and feature a significantly large surface area, drastically reducing the time required for antibody adsorption. With proficient handling, the antibody adsorption process can be completed within 30 minutes, and the entire antibody purification workflow can be finished within 1 hour.

Immunocytokines

As a leading supplier of recombinant antibodies, Creative Biolabs provides a wide range of GMP-grade products, committed to delivering consistent, safe, and traceable reagent supplies for therapeutic manufacturers. Currently, we have developed a series of high-quality AbPlus immunocytokine products aimed at facilitating the development of immunotherapy drugs. We offer a diverse array of high-purity, high-activity immunocytokine products with multiple species and tag options, covering nearly all cytokine families. Our immune cytokine products uniquely combine the specificity of monoclonal antibodies with the efficacy of cytokines, innovatively introducing multiple cytokines to target cells, while significantly enhancing anti-tumor effects.

Immunotoxins

Our AbPlus immunotoxin products combine targeting and cytotoxicity, offering a revolutionary solution for cancer treatment. By precisely designed toxins linked with specific antibodies, Creative Biolabs can selectively target and destroy cancer cells while significantly minimizing damage to normal cells. Nowadays, we offer immunotoxins that include both monoclonal and polyclonal antibodies against various types of cytotoxic proteins. Moreover, with superior research performance and competitive market pricing, our immunotoxin products deliver exceptional value for our customers, making them suitable for various medical settings.

Schematic Illustration of Each Assay Step and the Respective Time Frame. Fig.2 An Antibody Magnetic Beads Assay.2,3

Features

  • Highly efficient antibody binding capacity with extremely low non-specific adsorption.
  • Easy, time-saving, and gentle operation.
  • Fully in-house produced antibodies with batch-to-batch consistency.
  • High biological activity.
  • Quality control for microbiological and mycoplasma testing.
  • High purity, with SDS-PAGE results above 95%.

Creative Biolabs has established multiple world-class antibody platforms, ensuring that the AbPlus series antibody products have access to cutting-edge technologies and methodologies. We ensure that each AbPlus product type possesses excellent specificity and high affinity, enabling effective identification of target molecules and guaranteeing the accuracy of experimental results. We sincerely invite you to contact us for more information about our AbPlus antibody products.

References
  1. Rybchenko, Vladislav S., et al. "Targeted cytokine delivery for cancer treatment: engineering and biological effects." Pharmaceutics 15.2 (2023): 336.
  2. Ecke, Alexander, et al. "A rapid magnetic bead-based immunoassay for sensitive determination of diclofenac." Analytical and Bioanalytical Chemistry (2022): 1-11.
  3. Distributed under Open Access license CC BY 4.0, without modification.

For Research Use Only. Not For Clinical Use.

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