Recombinant Anti-EGFR × Anti-CD2 Bispecific Antibody (F(ab')2) (CAT#: FAB-L057)

Recombinant Anti-EGFR × Anti-CD2 Bispecific Antibody (F(ab')2) is a chemical conjugate composed of the Fab' of the anti-EGFR monoclonal antibody and Fab' of an antibody specific for CD2. A stable thioether linkage is formed between the two Fab'. This BsAb can retarget of T cells to tumor cells. It was designed for the treatment of Epithelial tumors.

  • Datasheet
  • MSDS
  • COA

Specifications

  • Target
  • EGFR & CD2
  • Type
  • F(ab')2
  • Species Reactivity
  • Human
  • Target 1
  • EGFR
  • Host Species 1
  • Mouse
  • Clone 1
  • 425
  • Target 2
  • CD2
  • Host Species 2
  • Mouse
  • Clone 2
  • --
  • Purity
  • >95% judged by SDS-PAGE under reducing condition
  • Application
  • FuncS, Promising therapeutic agent
  • Related Disease
  • Epithelial tumors

Target

  • Target 1
  • EGFR
  • Alternative Names
  • EGFR; epidermal growth factor receptor; ERBB; HER1; mENA; ERBB1; PIG61; NISBD2; proto-oncogene c-ErbB-1; cell growth inhibiting protein 40; erb-b2 receptor tyrosine kinase 1; cell proliferation-inducing protein 61; receptor tyrosine-protein kinase erbB-1;
  • Target 2
  • CD2
  • Alternative Names
  • CD2; CD2 molecule; T11; SRBC; LFA-2; T-cell surface antigen CD2; LFA-3 receptor; rosette receptor; erythrocyte receptor; lymphocyte-function antigen-2; T-cell surface antigen T11/Leu-5; CD2 antigen (p50), sheep red blood cell receptor

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

* Abbreviations
3D IHC3D Immunohistochemistry
ActivActivation
AgonistAgonist
ApopApoptosis
BABioassay
BIBioimaging
BlockBlocking
Cell ScreeningCell Screening
SeparationCell Separation
ChIPChromatin Immunoprecipitation
CMCDComplement Mediated Cell Depletion
CostimCostimulation
CytCytotoxicity
DepletionDepletion
DBDot Blot
EMElectron Microscopy
ELISAEnzyme-linked Immunosorbent Assay
ELISPOTEnzyme-linked Immunosorbent Spot
FCFlow Cytometry
FuncSFunctional Assay
GSGel Super Shift Assay
HAHemagglutination
IAImmunoassay
IBImmunoblotting
ICCImmunocytochemistry
IDImmunodiffusion
IFImmunofluorescence
IHCImmunohistochemistry
IHC-FrImmunohistochemistry-Frozen
IHC-PImmunohistochemistry-Paraffin
REImmunohistology - Resin Sections
IPImmunoprecipitation
IRMAImmunoradiometric Assay
SHIn situ hybridization
InhibInhibition
ICFCIntracellular Staining for Flow Cytometry
KO/KD-WBKnockout/Knockdown target confirmation by Western Blot
Live cell imagingLive cell imaging
CyTOF®Mass Cytometry
MeDIPMethylated DNA Immunoprecipitation
MultiplexMultiplex bead-based assay
NeutNeutralization
PPProtein Purification
PGProteogenomics
RIRadial Immunodiffusion
RIARadioimmunoassay
StimStimulation
SPRSurface Plasmon Resonance
TCTissue Culture
TBTurbidimetry
WBWestern Blot

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