Products

Anti-EGFR × Anti-CD2 Bispecific Antibody (FAB-L057)

Recombinant Anti-EGFR × Anti-CD2 Bispecific Antibody (F(ab')2) is a chemical conjugate composed of the Fab' of the anti-EGFR monoclonal antibody and Fab' of an antibody specific for CD2. A stable thioether linkage is formed between the two Fab'. This BsAb can retarget of T cells to tumor cells. It was designed for the treatment of Epithelial tumors.      

  • Datasheet

Specifications
Targets
EGFR & CD2
Type
F(ab')2
Species Reactivity
Human
Target 1
EGFR
Host
Mouse
Clone
425
Target 2
CD2
Host
Mouse
Clone
--
Purity
>95% judged by SDS-PAGE under reducing condition
Applications
FuncS, Promising therapeutic agent
Related Disease
Epithelial tumors
Targets
Target 1
EGFR
Gene ID
1956
UniProt ID
P00533
Alternative Names
EGFR; epidermal growth factor receptor; ERBB; HER1; mENA; ERBB1; PIG61; NISBD2
Target 2
CD2
Gene ID
914
UniProt ID
P06729
Alternative Names
CD2; CD2 molecule; T11; SRBC; LFA-2; T-cell surface antigen CD2; LFA-3 receptor; rosette receptor; erythrocyte receptor; lymphocyte-function antigen-2; T-cell surface antigen T11/Leu-5; CD2 antigen (p50), sheep red blood cell receptor

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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