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Anti-Thyroglobulin × Anti-TPO Bispecific Antibody (TAND-L058)

Recombinant Anti-Thyroglobulin × Anti-TPO Bispecific Antibody (TandAb) is a bispecific fusion protein with four binding sites, two of which bind to antigens of one kind of cells and the other two to the other kind of cells. This BsAb binds to thyroglobulin as well as thyroid peroxidase, which blocks the synthesis of thyroid hormones. It was designed for the treatment of Autoimmune thyroid disease.      

Specifications
Targets
Thyroglobulin & TPO
Type
TandAb
Expression Host
CHO
Species Reactivity
Human
Target 1
Thyroglobulin
Host
Human
Target 2
TPO
Host
Human
Purity
>95% judged by SDS-PAGE under reducing condition
Applications
FuncS, Promising therapeutic agent
Related Disease
Autoimmune thyroid disease
Targets
Target 1
Thyroglobulin
Gene ID
7038
UniProt ID
P01266
Alternative Names
AITD3N, TG; thyroglobulin
Target 2
TPO
Gene ID
7173
UniProt ID
P07202
Alternative Names
MSA; TPX; TDH2A

For lab research use only, not for diagnostic, therapeutic or any in vivo human use.

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