H-2Db/SV40 large T antigen (SAINNYAQKL) MHC Monomer (CAT#: MHC-YF210)
This product is a MHC monomer of biotinylated peptide/MHC complex composed large T antigen-derived peptide of SAINNYAQKL sequence covering 206-215 and H-2Db molecule. The pMHC monomer recognizes human CD8 T cells and can be used in the MHC tetramer analysis of individual antigen-specific T cells.
Specific Inquiry
Specifications
- Allele
- H-2Db
- Class
- Class I
- Antigen
- large T antigen
- Antigen Species
- SV40
- Peptide
- SAINNYAQKL
- Range
- 206-215
- Conjugate
- Biotin
- Application
- MHC Multimer
Target
- Antigen Introduction
- SV40 large T antigen (Simian Vacuolating Virus 40 TAg) is a hexamer protein that is a dominant-acting oncoprotein derived from the polyomavirus SV40. TAg is capable of inducing malignant transformation of a variety of cell types. The transforming activity of TAg is due in large part to its perturbation of the retinoblastoma (pRb) and p53 tumor suppressor proteins. In addition, TAg binds to several other cellular factors, including the transcriptional co-activators p300 and CBP, which may contribute to its transformation function.
- Alternative Names
- SV40 Large T;Simian virus 40 large T antigen
- Gene ID
- 29031019
- UniProt ID
- P03070
Downloads
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Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1976MZ | Recombinant Mouse Anti-Simian Virus 40 (SV40 SV40gp6 Antibody (clone MQ8O) | IHC-Fr | Mouse antibody |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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