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CACNG5

CACNG5 (Calcium Voltage-Gated Channel Auxiliary Subunit Gamma 5) is a Protein Coding gene. Diseases associated with CACNG5 include Bipolar Disorder and Schizophrenia. Among its related pathways are Cardiac conduction and NFAT and Cardiac Hypertrophy. Gene Ontology (GO) annotations related to this gene include voltage-gated calcium channel activity and ion transmembrane transporter activity. An important paralog of this gene is CACNG7.
Protein class

FDA approved drug targets

Predicted location

Membrane

Single cell type specificity

Cell type enriched (Oligodendrocyte precursor cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Not detected

Interaction

The L-type calcium channel is composed of five subunits: alpha-1, alpha-2/delta, beta and gamma. Acts as an auxiliary subunit for AMPA-selective glutamate receptors (AMPARs). Found in a complex with GRIA1, GRIA2, GRIA3, GRIA4, CNIH2, CNIH3, CACNG2, CACNG3, CACNG4, CACNG7 and CACNG8. Interacts with GRIA1, GRIA2, GRIA3 and GRIA4 (By similarity).

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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