Transporters
Intracellular, Membrane (different isoforms)
Group enriched (Cardiomyocytes, Cytotrophoblasts, Extravillous trophoblasts, Hofbauer cells, Syncytiotrophoblasts, Adipocytes, Fibroblasts)
Low immune cell specificity
Low cell line specificity
Component of the Golgi to ER traffic (GET) complex, which is composed of GET1/WRB, CAMLG/GET2 and GET3/TRC40 (PubMed:21444755, PubMed:23041287, PubMed:24392163, PubMed:32910895). Within the complex, GET1 and CAMLG form a heterotetramer which is stabilized by phosphatidylinositol binding and which binds to the GET3 homodimer (PubMed:32910895). Interacts with CAMLG (via C-terminus) (PubMed:23041287, PubMed:31417168, PubMed:32187542). GET3 shows a higher affinity for CAMLG than for GET1 (PubMed:24392163).
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For Research Use Only. Not For Clinical Use.