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CLCNKA

Chloride channels are a superfamily of poorly understood ion channels specific for chloride. These channels may conduct many different ions, but are named for chloride because its concentration in vivo is much higher than other anions. Several families of voltage-gated channels and ligand-gated channels (e.g., the CaCC families) have been characterized in humans.
Protein class

Disease related genes, Human disease related genes

Predicted location

Membrane

Single cell type specificity

Cell type enriched (Late spermatids)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enriched (U-266/70)

Interaction

Homodimer (PubMed:17562318). Interacts with BSND. Forms heteromers with BSND in the thin ascending limb of Henle (By similarity).

Molecular function

Chloride channel, Ion channel, Voltage-gated channel

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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