Cancer-related genes, Plasma proteins, Transporters
Intracellular
Low cell type specificity
Low immune cell specificity
Low cell line specificity
Interacts with H2A, H2B, H3 and H4 histones (By similarity). Forms a heterodimer with KPNB1. Interacts with KPNB1, SNUPN, XPO1, RPL23A, RPS7, and RPL5. Binds directly to nuclear pore complexes (By similarity). Interacts with H2A, H2B, H3 and H4 histones. Interacts with SMAD4 and NUP93; translocates SMAD4 to the nucleus through the NPC upon BMP7 stimulation resulting in activation of SMAD4 signaling (PubMed:26878725). (Microbial infection) Interacts with HIV-1 reverse transcription complex integrase and rev.
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For Research Use Only. Not For Clinical Use.