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KRT12
KRT12 encodes the type I intermediate filament chain keratin 12, expressed in corneal epithelia. Mutations in this gene lead to Meesmann corneal dystrophy.
Protein class
Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Group enriched (Paneth cells, Distal enterocytes)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Not detected
Interaction
Heterotetramer of two type I and two type II keratins. Keratin-3 associates with keratin-12.
More Types Infomation
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: WB
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgM
- Application: WB, IHC, FC ELISA
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For Research Use Only. Not For Clinical Use.