CD markers
Intracellular, Membrane (different isoforms)
Cell type enhanced (Hofbauer cells, Macrophages, granulocytes, dendritic cells, Kupffer cells, NK-cells)
Low immune cell specificity
Group enriched (HMC-1, Karpas-707, THP-1)
Interacts with SH2 domains of tyrosine-protein phosphatases PTPN6 and PTPN11. The interaction with PTPN6 is constitutive. Interacts with the SH2 domain of CSK. Binds with high affinity to extracellular matrix collagens, the interaction is functionally important.
Receptor
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For Research Use Only. Not For Clinical Use.