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LMCD1

This gene encodes a member of the LIM-domain family of zinc finger proteins. The encoded protein contains an N-terminal cysteine-rich domain and two C-terminal LIM domains. The presence of LIM domains suggests involvement in protein-protein interactions. The protein may act as a co-regulator of transcription along with other transcription factors. Alternate splicing results in multiple transcript variants of this gene.
Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Adipocytes, Endothelial cells, Ductal cells, Pancreatic endocrine cells, Smooth muscle cells)

Immune cell specificity

Immune cell enriched (T-reg)

Cell line specificity

Cell line enhanced (HHSteC, HSkMC, hTEC/SVTERT24-B, U-2197)

Interaction

Interacts with GATA1 and GATA4 (By similarity). Interacts with beta-dystroglycan. Interacts with GATA6.

Molecular function

Repressor

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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