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TAF1L

This locus is intronless, and apparently arose in the primate lineage from retrotransposition of the transcript from the multi-exon TAF1 locus on the X chromosome. The gene is expressed in male germ cells, and the product has been shown to function interchangeably with the TAF1 product.
Protein class

Plasma proteins

Predicted location

Intracellular

Single cell type specificity

Group enriched (Bipolar cells, Early spermatids)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Not detected

Interaction

Can bind directly to TATA-box binding protein (TBP). Interacts (via bromo domains) with acetylated lysine residues on the N-terminus of histone H1. 4, H2A, H2B, H3 and H4 (in vitro).

Molecular function

DNA-binding

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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