Plasma proteins
Intracellular
Cell type enhanced (Early spermatids, Microglial cells, Alveolar cells type 1, Late spermatids)
Low immune cell specificity
Cell line enhanced (HAP1, HUVEC TERT2, TIME)
Homodimer. Interacts with the syntrophins SNTA1; SNTB1 and SNTB2. Interacts with SYNM. Interacts (via its WWW and ZZ domains) with DAG1 (via the PPXY motif of betaDAG1); the interaction is inhibited by the tyrosine phosphorylation of the PPXY motif of DAG1. Interacts with DTNB (By similarity). Interacts with PGM5 (By similarity).
Actin-binding
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For Research Use Only. Not For Clinical Use.