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Recombinant Mouse anti-Human CYP7B1 Monoclonal antibody (2B11) (CAT#: MOB-0126CT)

Recombinant Mouse monoclonal antibody to Human CYP7B1, expressed in Chinese Hamster Ovary cells(CHO).


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Normal Tissue
Figure 1 IHC staining of human small intestine
Figure 1 IHC staining of human small intestine
(Immunohistochemical staining of human small intestine shows strong membranous, and cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/17761/ihc_selected.jpg
Figure 2 Cerebral cortex
Figure 2 Cerebral cortex
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glial cells Staining: Medium Intensity: Strong Quantity: <25% Location: Cytoplasmic/ membranous Neuronal cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/17761/42992_B_8_5.jpg
Figure 3 Colon
Figure 3 Colon
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/17761/42992_A_7_3.jpg
Figure 4 Liver
Figure 4 Liver
(Cholangiocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/17761/42992_A_9_4.jpg
Figure 5 Kidney
Figure 5 Kidney
(Cells in glomeruli Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/17761/42992_A_8_5.jpg
Figure 6 Testis
Figure 6 Testis
(Cells in seminiferous ducts Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/17761/42992_A_4_6.jpg
Figure 7 Lymph node
Figure 7 Lymph node
(Germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear Non-germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/17761/42992_A_7_8.jpg
RNA Expression
Figure 8 RNA cell line category: Group enriched (HSkMC, SH-SY5Y, WM-115)
Figure 8 RNA cell line category: Group enriched (HSkMC, SH-SY5Y, WM-115)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000172817-CYP7B1

Specifications

  • Immunogen
  • Recombinant fragment: CDNNKFISEL RDDFLKFDDK FAYLVSNIPI ELLGNVKSIR EKIIKCFSSE KLAKMQGWSE VFQSRQDVLE KYYVHEDLEI GAHH, corresponding to amino acids 203-286 of human CYP7B1with a 26 kDa tag.
  • Host Species
  • Mouse
  • Species Reactivity
  • Human
  • Clone
  • 2B11
  • Applications
  • Used for immunoassay techniques such as: Enzyme-linked Immunosorbent Assay; Western Blot
  • Conjugate
  • Unconjugated

Product Property

  • Purity
  • Protein A purified
  • Format
  • Liquid
  • Concentration
  • 1.0 mg/ml
  • Buffer
  • Preservative: None Constituents: 1X PBS, pH 7.2
  • Storage
  • Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.

Target

  • Alternative Names
  • CYP7B1; cytochrome P450, family 7, subfamily B, polypeptide 1; CP7B; CBAS3; SPG5A; 25-hydroxycholesterol 7-alpha-hydroxylase; cytochrome P450 7B1; oxysterol 7alpha-hydroxylase; oxysterol 7-alpha-hydroxylase; cytochrome P450, subfamily VIIB (oxysterol 7 alpha-hydroxylase), polypeptide 1;
  • UniProt ID
  • Function
  • 25-hydroxycholesterol 7alpha-hydroxylase activity; electron carrier activity; heme binding; metal ion binding; monooxygenase activity; oxysterol 7-alpha-hydroxylase activity;

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-0912 Hi-Affi™ Rabbit Anti-CYP7B1 Recombinant Antibody (clone DS912AB) WB Rabbit IgG

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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