Mouse Anti-MMP9 Recombinant Antibody (clone SDS3) (CAT#: PABC-174)
Recombinant Mouse Antibody (SDS3) is capable of binding to MMP9. SDS3 inhibited MMP9 and its close analog MMP-2.
Specific Inquiry
IF
Figure 1 SDS3 promotes CD8+ T cell activation and T cell infiltration.
Immunofluorescence images of 9-wk-old MMTV-PyMT lungs i.v. injected with 1 × 105 VO-PyMT-GFP-Luc cells 3 wk after SDS3 treatment.
Owyong, M., Chou, J., van den Bijgaart, R. J., Kong, N., Efe, G., Maynard, C., ... & Headley, M. (2019). MMP9 modulates the metastatic cascade and immune landscape for breast cancer anti-metastatic therapy. Life science alliance, 2(6).
IF
Figure 2 MMP9 is present in cells within the metastatic microenvironment.
Whole-mount lung fluorescence imaging of lung metastases in MMTV-PyMT mice treated with IgG.
Owyong, M., Chou, J., van den Bijgaart, R. J., Kong, N., Efe, G., Maynard, C., ... & Headley, M. (2019). MMP9 modulates the metastatic cascade and immune landscape for breast cancer anti-metastatic therapy. Life science alliance, 2(6).
FC
Figure 3 SDS3 promotes CD8+ T cell activation and T cell infiltration.
Representative scatterplot of ICOS+ CD8 T-cell expression of PD-1. Red box represents IgG-treated activated CD8 T cells expressing PD-1. Green box represents SDS3-treated activated CD8 T cells expressing PD-1.
Owyong, M., Chou, J., van den Bijgaart, R. J., Kong, N., Efe, G., Maynard, C., ... & Headley, M. (2019). MMP9 modulates the metastatic cascade and immune landscape for breast cancer anti-metastatic therapy. Life science alliance, 2(6).
Specifications
- Host Species
- Mouse
- Derivation
- Mouse
- Type
- Mouse IgG
- Specificity
- Human MMP9
- Species Reactivity
- Human
- Clone
- SDS3
- Applications
- IF, FC
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been reported for use in Immunofluorescence and Flow Cytometry.
Target
- Alternative Names
- MMP9; matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase); GELB; CLG4B; MMP9; MANDP2; matrix metalloproteinase-9; type V collagenase; macrophage gelatinase; matrix metalloproteinase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
- Gene ID
- 4318
- UniProt ID
- P14780
Related Resources
TNF Signaling Pathway
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone SDS3"
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Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-533CL | Anti-Human MMP9 Recombinant Antibody (GS-5745) | WB, Inhib | Antibody |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0824CL | Human Anti-MMP9 Recombinant Antibody (TAB-0824CL) | ELISA | Human IgG4 |
| TAB-0824CL-S(P) | Human Anti-MMP9 Recombinant Antibody; scFv Fragment (TAB-0824CL-S(P)) | ELISA | Human scFv |
| TAB-0825CL-S(P) | Human Anti-MMP9 Recombinant Antibody; scFv Fragment (TAB-0825CL-S(P)) | ELISA | Human scFv |
| TAB-0824CL-F(E) | Human Anti-MMP9 Recombinant Antibody; Fab Fragment (TAB-0824CL-F(E)) | ELISA | Human Fab |
| TAB-0825CL-F(E) | Human Anti-MMP9 Recombinant Antibody; Fab Fragment (TAB-0825CL-F(E)) | ELISA | Human Fab |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0826CL | Mouse Anti-MMP9 Recombinant Antibody (TAB-0826CL) | Inhib, ELISA, IHC | Mouse IgG |
| TAB-0827CL | Mouse Anti-MMP9 Recombinant Antibody (TAB-0827CL) | ELISA | Mouse IgG |
| TAB-0826CL-S(P) | Mouse Anti-MMP9 Recombinant Antibody; scFv Fragment (TAB-0826CL-S(P)) | ELISA | Mouse scFv |
| TAB-0827CL-S(P) | Mouse Anti-MMP9 Recombinant Antibody; scFv Fragment (TAB-0827CL-S(P)) | ELISA | Mouse scFv |
| TAB-0826CL-F(E) | Mouse Anti-MMP9 Recombinant Antibody; Fab Fragment (TAB-0826CL-F(E)) | ELISA | Mouse Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBC-174 | Mouse Anti-MMP9 Recombinant Antibody (clone SDS3); scFv Fragment | ELISA, Neut | Mouse scFv |
| HPAB-0027-YC-S(P) | Mouse Anti-MMP9 Recombinant Antibody; scFv Fragment (HPAB-0027-YC-S(P)) | FC | Mouse scFv |
| HPAB-0028-YC-S(P) | Human Anti-MMP9 Recombinant Antibody (clone G03-VH-GL-V1/ G06-VL-GL1); scFv Fragment | Neut | Human scFv |
| HPAB-0513LY-S(P) | Mouse Anti-MMP9 Recombinant Antibody (clone M4); scfv Fragment | FC | Mouse scfv |
| HPAB-0514LY-S(P) | Mouse Anti-MMP9 Recombinant Antibody (clone M12); scfv Fragment | FC | Mouse scfv |
Chicken IgY Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0717MZ | Chicken Anti-MMP9 Polyclonal IgY | WB | Chicken antibody |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1748CQ | Recombinant Mouse Anti-MMP9 Antibody (VMC204) | Inhib, IHC-Fr, IP, IHC-P, WB, IHC, ICC | IgG1 |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2263 | Hi-Affi™ Recombinant Rabbit Anti-MMP9 Monoclonal Antibody (DS2263AB) | FC, IHC-P, WB | IgG |
| MOR-4331 | Hi-Affi™ Recombinant Rabbit Anti-MMP-9 Monoclonal Antibody (SI420DS) | ELISA | IgG |
| MOR-4332 | Hi-Affi™ Recombinant Rabbit Anti-MMP-9 Monoclonal Antibody (SI421DS) | ELISA | IgG |
Chimeric Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-002ML | Anti-Human MMP9 Recombinant Antibody (Andecaliximab) | ELISA, IHC, FC, IP, IF, FuncS | IgG4, κ |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0027-YC-F(E) | Mouse Anti-MMP9 Recombinant Antibody; Fab Fragment (HPAB-0027-YC-F(E)) | FC | Mouse Fab |
| HPAB-0028-YC-F(E) | Human Anti-MMP9 Recombinant Antibody (clone G03-VH-GL-V1/ G06-VL-GL1); Fab Fragment | Neut | Human Fab |
| HPAB-0199-FY-F(E) | Human Anti-MMP9 Recombinant Antibody (clone DX-2802); Fab Fragment | ELISA, FC | Human Fab, λ |
| HPAB-0200-FY-F(E) | Human Anti-MMP9 Recombinant Antibody (clone M0279-A03); Fab Fragment | ELISA, FC | Human Fab |
| HPAB-1320-FY-S(P) | Human Anti-MMP9 Recombinant Antibody; scFv Fragment (HPAB-1320-FY-S(P)) | Activ | Human scFv |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0513LY | Mouse Anti-MMP9 Recombinant Antibody (clone M4) | FC | Mouse IgG |
| HPAB-0514LY | Mouse Anti-MMP9 Recombinant Antibody (clone M12) | FC | Mouse IgG |
| HPAB-M0311-YC | Mouse Anti-MMP9 Recombinant Antibody (clone AB0046) | ELISA, FuncS | Mouse IgG1, κ |
| HPAB-1320-FY | Human Anti-MMP9 Recombinant Antibody (HPAB-1320-FY) | Activ | Human IgG |
| ZG-0728F | Mouse Anti-MMP9 Recombinant Antibody (clone 4A3) | WB, IHC-P | Mouse IgG1 |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-002ML | Afuco™ Anti-MMP9 ADCC Recombinant Antibody (Andecaliximab), ADCC Enhanced | ELISA, IHC, FC, IP, IF, FuncS | ADCC enhanced antibody |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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