Mouse Anti-MPTS Recombinant Antibody (clone 6C8) (CAT#: PABL-277)

Recombinant mouse antibody (6C8) is capable of binding to MPTS. The antibody 6C8 binds MPTS with the dissociation constant KD=600±100 nM.


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Figure 1 Repertoire of proteins recognized by each anti-MPTS Ab as determined by ELISA.

Figure 1 Repertoire of proteins recognized by each anti-MPTS Ab as determined by ELISA.

The 45 randomly selected proteins (see Figure 2) are arranged according to the affinity with which they are bound by 6C8. Data were collected in triplicate and bars represent average absorbance normalized by Ab concentration.

Adhikary, R., Yu, W., Oda, M., Walker, R. C., Chen, T., Stanfield, R. L.,... & Romesberg, F. E. (2015). Adaptive mutations alter antibody structure and dynamics during affinity maturation. Biochemistry, 54(11), 2085-2093.

Figure 2 The 45 randomly selected proteins for ELISA.

Figure 2 The 45 randomly selected proteins for ELISA.

Adhikary, R., Yu, W., Oda, M., Walker, R. C., Chen, T., Stanfield, R. L.,... & Romesberg, F. E. (2015). Adaptive mutations alter antibody structure and dynamics during affinity maturation. Biochemistry, 54(11), 2085-2093.

Figure 3 3PEPS decays for Abs 6C8, 8B10, and 6C6 (symbols, data points; lines, best fit to data).

Figure 3 3PEPS decays for Abs 6C8, 8B10, and 6C6 (symbols, data points; lines, best fit to data).

Adhikary, R., Yu, W., Oda, M., Walker, R. C., Chen, T., Stanfield, R. L.,... & Romesberg, F. E. (2015). Adaptive mutations alter antibody structure and dynamics during affinity maturation. Biochemistry, 54(11), 2085-2093.


Specifications

  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Host Species
  • Mouse
  • Derivation
  • Mouse
  • Type
  • Mouse IgG
  • Clone
  • 6C8
  • Applications
  • ELISA, FuncS

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • MPTS; 8-methoxypyrene-1,3,6-trisulfonate

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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