Camelid Anti-BCL2 Recombinant Single Domain Antibody (HPAB-0681-YJ-VHH) (CAT#: HPAB-0681-YJ-VHH)
This product is a recombinant Llama single domain antibody that recognizes Human BCL2.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line SK-MEL-30
(Immunofluorescent staining of human cell line SK-MEL-30 shows localization to nucleoplasm & nuclear membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/55295/1484_G3_6_selected.jpg
(Immunofluorescent staining of human cell line SK-MEL-30 shows localization to nucleoplasm & nuclear membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/55295/1484_G3_6_selected.jpg
Figure 2 Thyroid gland
(Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3/155167_B_3_5.jpg
(Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3/155167_B_3_5.jpg
Figure 3 Colon
(Mucosal lymphoid cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Peripheral nerve/ganglion
Staining: High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3/155167_A_7_3.jpg
(Mucosal lymphoid cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Peripheral nerve/ganglion
Staining: High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3/155167_A_7_3.jpg
Figure 4 Kidney
(Cells in tubules
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3/155167_A_8_5.jpg
(Cells in tubules
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3/155167_A_8_5.jpg
Figure 5 Lymph node
(Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3/155167_A_7_8.jpg
(Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3/155167_A_7_8.jpg
Figure 6 RNA cell line category: Cell line enhanced (HDLM-2, HL-60, Karpas-707, U-266/70)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000171791-BCL2
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000171791-BCL2
Specifications
- Immunogen
- Human protein extract
- Host Species
- Camelid
- Derivation
- Phage display library
- Type
- Camelid VHH
- Specificity
- Human
- Species Reactivity
- Human
- Clone
- HPAB-0681-YJ-VHH
- Applications
- ELISA
- Related Disease
- Cancer
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been reported for use in Enzyme-linked Immunosorbent Assay.
Target
- Alternative Names
- Bcl-2; PPP1R50; apoptosis regulator Bcl-2; B-cell CLL/lymphoma 2; protein phosphatase 1, regulatory subunit 50
- Gene ID
- 596
- UniProt ID
- P10415
Related Resources
Hedgehog Signaling Pathway
p53 Signaling Pathway
Prostate Cancer
AGE-RAGE Signaling Pathway in Diabetic Complications
Amyotrophic Lateral Sclerosis
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "BCL2"
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-103-F(E) | Recombinant Anti-dog BCL2 Antibody Fab Fragment | WB, IP, FuncS | Fab |
| MHH-103-F(E) | Recombinant Human Anti-dog BCL2 Antibody Fab Fragment | IP, IF, Biosensors, FuncS | Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-103-S(P) | Recombinant Anti-dog BCL2 Antibody scFv Fragment | ELISA, WB, FuncS | scFv |
| MHH-103-S(P) | Recombinant Human Anti-dog BCL2 Antibody scFv Fragment | ELISA, IF, FuncS | scFv |
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NABL-053 | Recombinant Anti-human BCL2 VHH Single Domain Antibody | WB, ELISA, IP, FuncS | Llama VHH |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHH-103 | Recombinant Human Anti-dog BCL2 Antibody | RIA, ELISA, FuncS | IgG |
| MRO-0158-CN | Mouse Anti-BCL2 Recombinant Antibody (clone 9F1) | WB, IHC | Mouse IgG |
| MRO-0159-CN | Mouse Anti-BCL2 Recombinant Antibody (clone F7-1-A1) | WB, IF, IHC | Mouse IgG2b |
| MRO-0160-CN | Rabbit Anti-BCL2 Recombinant Antibody (clone CBACN-062) | WB, IF, IHC, IP, FC | Rabbit IgG |
| MRO-0161-CN | Rabbit Anti-BCL2 Recombinant Antibody (clone JF104-8) | WB, IF, IHC, FC | Rabbit IgG |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-041CQ | Mouse Anti-BCL2 Recombinant Antibody (clone CBL685) | Neut | Mouse IgG1 |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0342 | Hi-Affi™ Rabbit Anti-BCL2 Recombinant Antibody (clone DS342AB) | IHC-P | Rabbit IgG |
MHC Tetramer for Cancer
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-CN0405 | PE-A*02:01/Human BCL2 (PLFDFSWLSL) MHC Tetramer | FCM, IHC | |
| MHC-CN0406 | APC-A*02:01/Human BCL2 (PLFDFSWLSL) MHC Tetramer | FCM, IHC | |
| MHC-CN0407 | FITC-A*02:01/Human BCL2 (PLFDFSWLSL) MHC Tetramer | FCM, IHC | |
| MHC-CN0408 | A*02:01/Human BCL2 (PLFDFSWLSL) MHC Tetramer | FCM, IHC | |
| MHC-CN0409 | PE-A*02:01/Human BCL2 (WLSLKTLLSL) MHC Tetramer | FCM, IHC |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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