Mouse Anti-Lung adenocarcinoma Recombinant Antibody (clone KS1/4) (CAT#: HPAB-0036-YJ)
This product is a recombinant mouse antibody that recognizes human lung adenocarcinoma. Mab KS1/4 is useful for the diagnosis, prognosis and treatment of disease states including adenocarcinoma.
Specific Inquiry
IHC
Figure 1 Expression of KSl/4-reactive antigen by the carcinoma.
Immunostained with MoAb KS1/4. The overlying dermis is not stained.
Elias, D. J., Hirschowitz, L., Kline, L. E., Kroener, J. F., Dillman, R. O., Walker, L. E., ... & Timms, R. M. (1990). Phase I clinical comparative study of monoclonal antibody KS1/4 and KS1/4-methotrexate immunconjugate in patients with non-small cell lung carcinoma. Cancer research, 50(13), 4154-4159.
IHC
Figure 2 Posttreatment carcinoma biopsies immunostained for MoAb KS 1/4 .
MoAb KS1/4 is bound to carcinoma. Immunostained with goat anti-mouse antibody. The overlying dermis is not stained.
Elias, D. J., Hirschowitz, L., Kline, L. E., Kroener, J. F., Dillman, R. O., Walker, L. E., ... & Timms, R. M. (1990). Phase I clinical comparative study of monoclonal antibody KS1/4 and KS1/4-methotrexate immunconjugate in patients with non-small cell lung carcinoma. Cancer research, 50(13), 4154-4159.
IP
Figure 3 Immunoprecipitations
Line B, D: MoAb KS1/4
Varki, N. M., Reisfeld, R. A., & Walker, L. E. (1984). Antigens associated with a human lung adenocarcinoma defined by monoclonal antibodies. Cancer research, 44(2), 681-687.
IF
Figure 4 Immunofluorescence staining patterns of the cell line UCLA-P3 derived from an adenocarcinoma of the lung (×400).
Staining with MoAb KS1/4.
Varki, N. M., Reisfeld, R. A., & Walker, L. E. (1984). Antigens associated with a human lung adenocarcinoma defined by monoclonal antibodies. Cancer research, 44(2), 681-687.
Specifications
- Host Species
- Mouse
- Type
- Mouse IgG2a, κ
- Specificity
- Human Lung adenocarcinoma
- Species Reactivity
- Human
- Clone
- KS1/4
- Applications
- ELISA, IP, IF, IHC
- Related Disease
- Cancer
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The antibody KS1/4 has been reported in applications of Enzyme-linked Immunosorbent Assay, Immunoprecipitation, Immunofluorescence, Immunohistochemistry. It's recommended that the optimal antibody concentration, dilution, incubition time etc. be carefully titrated in specific assays.
Target
- Alternative Names
- Lung Adenocarcinoma Cells; KS1/4
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0036-YJ-S(P) | Mouse Anti-Lung adenocarcinoma Recombinant Antibody (clone KS1/4); scFv Fragment | ELISA, IP, IF | Mouse scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0036-YJ-F(E) | Mouse Anti-Lung adenocarcinoma Recombinant Antibody (clone KS1/4); Fab Fragment | ELISA, IP, IF | Mouse Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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