Human Anti-PfMSP1 Recombinant Antibody (clone mAb10) (CAT#: VS-0623-WK22)

The antibody clone mAb10 was produced by immunizing with Full-length Pf merozoite surface protein 1. mAb10 has higher antigen-binding affinity. It can be used for detection of Plasmodium falciparum MSP1 in ELISA, WB and IF staining.


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Inhib

Figure 1 <em>P. falciparum</em> growth inhibition by six select mAbs.

Figure 1 P. falciparum growth inhibition by six select mAbs.

Inhibition was calculated relative to a negative control (antibody elution buffer that was buffer exchanged to PBS alongside purified antibodies). mAb 481A, an anti-PfAMA1 mAb with confirmed growth-inhibitory activity, served as a positive control.

ELISA

Figure 2 The binding strength of mAb10 and mAb22 as determined by chaotropic ELISA.

Figure 2 The binding strength of mAb10 and mAb22 as determined by chaotropic ELISA.

Binding strength (IC50) is defined as the concentration of urea that results in loss of 50% of mAb binding.


Specifications

  • Immunogen
  • Full-length Pf merozoite surface protein 1
  • Host Species
  • Human
  • Derivation
  • Isolated from PfMSP1-specific B cells
  • Type
  • Human IgG, kappa
  • Specificity
  • Plasmodium falciparum MSP1
  • Species Reactivity
  • Plasmodium falciparum
  • Clone
  • mAb10
  • Applications
  • ELISA, WB, IF, Inhib
  • Conjugate
  • Unconjugated
  • Related Disease
  • Malaria

Product Property

  • Clonality
  • Monoclonal
  • Purification
  • Affinity purified
  • Purity
  • >95% as determined by SDS-PAGE
  • Format
  • Liquid
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Buffer
  • PBS
  • Preservative
  • No Preservative
  • Storage
  • Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
  • Shipping
  • Ice packs

Target

  • Alternative Names
  • merozoite surface protein 1
  • Long Name
  • Merozoite surface protein 1

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "PfMSP1"

Recombinant Antibody

CAT Product Name Application Type
VS-0623-WK23 Human Anti-PfMSP1 Recombinant Antibody (clone mAb22) ELISA, WB, IF, Inhib Human IgG, lambda

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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