The antibody clone mAb10 was produced by immunizing with Full-length Pf merozoite surface protein 1. mAb10 has higher antigen-binding affinity. It can be used for detection of Plasmodium falciparum MSP1 in ELISA, WB and IF staining.
Figure 1 P. falciparum growth inhibition by six select mAbs.
Inhibition was calculated relative to a negative control (antibody elution buffer that was buffer exchanged to PBS alongside purified antibodies). mAb 481A, an anti-PfAMA1 mAb with confirmed growth-inhibitory activity, served as a positive control.
Figure 2 The binding strength of mAb10 and mAb22 as determined by chaotropic ELISA.
Binding strength (IC50) is defined as the concentration of urea that results in loss of 50% of mAb binding.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
VS-0623-WK23 | Human Anti-PfMSP1 Recombinant Antibody (clone mAb22) | ELISA, WB, IF, Inhib | Human IgG, lambda |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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