Human Anti-VACV A33R Recombinant Antibody (clone 461) (CAT#: FAMAB-0017JF)
Recombinant monoclonal antibody specially binds to VACV antigens A33R. This anti-VACV A33R monoclonal antibody 461 can be wildey used as an effective postexposure prophylaxis or treatment of disease caused by orthopoxviruses.
Specific Inquiry
Inhib
Figure 1 In vitro neutralization of EEV by a-V V-env. antiserum.
Each value represents the mean ± S.E.M. of duplicate measurements from at least four independent experiments.
Galmiche, M. C., Goenaga, J., Wittek, R., & Rindisbacher, L. (1999). Neutralizing and protective antibodies directed against vaccinia virus envelope antigens. Virology, 254(1), 71-80.
ELISA
Figure 2 Serum samples were taken from each mouse vaccinated with envelope proteins A33R before i.n. challenge with 107 pfu.
The OD490 nm values obtained by ELISA from the sera prechallenge and the relative body weights of the mice postchallenge are indicated.
Galmiche, M. C., Goenaga, J., Wittek, R., & Rindisbacher, L. (1999). Neutralizing and protective antibodies directed against vaccinia virus envelope antigens. Virology, 254(1), 71-80.
WB
Figure 3 Affinity-purified recombinant A33R, A34R, A56R, and B5R were analyzed under reducing conditions by using WB.
Stained gel with lanes corresponding to (M) marker proteins and the indicated EV proteins is shown.
García, A. D., Meseda, C. A., Mayer, A. E., Kumar, A., Merchlinsky, M., & Weir, J. P. (2007). Characterization and use of mammalian-expressed vaccinia virus extracellular membrane proteins for quantification of the humoral immune response to smallpox vaccines. Clinical and Vaccine Immunology, 14(8), 1032-1044.
Specifications
- Immunogen
- VACV particles
- Host Species
- Human
- Type
- Human IgG1
- Specificity
- Vaccinia virus A33R
- Species Reactivity
- VACV
- Clone
- 461
- Applications
- WB, ELISA, Inhib
- Related Disease
- Orthopoxvirus infection
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- The VACV A33R antibody has been reported in applications of Western Blot, Enzyme-linked Immunosorbent Assay, Inhibition.
Target
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone 461"
See other products for "VACV A33R"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-2680CQ | Recombinant Mouse Anti-VACV A33R Antibody (5E450) | ELISA, IHC, IF | Mouse antibody |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0017JF-F(E) | Human Anti-VACV A33R Recombinant Antibody (clone 461); Fab Fragment | FLISA, WB, ELISA, FACS, FuncS | Human Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| FAMAB-0017JF-S(P) | Human Anti-VACV A33R Recombinant Antibody (clone 461); scFv Fragment | FLISA, WB, ELISA, FACS, FuncS | Human scFv |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for FAMAB-0017JF. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.