Recombinant Llama Anti-Respiratory syncytial virus F Single Domain Antibody (VS-0923-FY252) (CAT#: VS-0923-FY252)
ALX-0171 is a therapeutic designed to combat Respiratory syncytial virus through inhalation. It is intended to be delivered directly to the lungs via nebulization, which is the site of Respiratory syncytial virus infection. Gontivimab (ALX-0171; VR-465) is a potent anti-Respiratory syncytial virus prefusion F protein mAb (llama-derived variable heavy-chain domain) with a KD value of 0.113 nM. It has demonstrated antiviral activity, with IC50s of 0.1 and 0.4 nM for Respiratory syncytial virus-A and Respiratory syncytial virus-B 18537 strain, respectively.
Specific Inquiry
Specifications
- Host Species
- Llama
- Type
- Llama variable heavy-chain domain
- Specificity
- Respiratory syncytial virus F
- Species Reactivity
- Respiratory syncytial virus
- Clone
- VS-0923-FY252
- Applications
- ELISA, Western Blot
- Conjugate
- Unconjugated
Product Property
- Purification
- Affinity purified
- Purity
- >95%
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Respiratory syncytial virus glycoprotein F; Respiratory syncytial virus F; ALX-0171; VR-465
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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