Secreted
Cell type enhanced (Microglial cells, Adipocytes, Inhibitory neurons, Hepatic stellate cells)
Immune cell enhanced (basophil)
Cell line enhanced (EFO-21, HUVEC TERT2, Karpas-707, SiHa, TIME, U-266/84)
Interacts with SOSTDC1 (By similarity). Interacts (when glycosylated) with type I receptor ACVR1 (PubMed:18070108). Interacts with type II receptor ACVR2B (PubMed:18070108). Interacts with Hemojuvelin/HJV (By similarity).
Cytokine, Developmental protein, Growth factor
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For Research Use Only. Not For Clinical Use.