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DRD1
This gene encodes the D1 subtype of the dopamine receptor. The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene.
Protein class
FDA approved drug targets, G-protein coupled receptors
Predicted location
Membrane
Single cell type specificity
Group enriched (Bipolar cells, Horizontal cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enriched (RT4)
Interaction
Interacts with DNAJC14 via its C-terminus (By similarity). Interacts with DRD2 (By similarity).
Molecular function
G-protein coupled receptor, Receptor, Transducer
More Types Infomation
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2b
- Application: WB, IP, IF, FuncS
- Rabbit Anti-DRD1 Recombinant Antibody (clone JM10-93) (MRO-0495-CN)
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IF, IHC
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For Research Use Only. Not For Clinical Use.